The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons (Q28594737)

31 January 2017

title

The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons (English)

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NIMA (never in mitosis gene a)-related expressed kinase 3

31 January 2017

0 references

1 reference

GOA release 2020-03-11

Robert H. Baloh

1 reference

31 January 2017

Jufang Chang

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31 January 2017

Jeffrey Milbrandt

series ordinal

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31 January 2017

language of work or name

English

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publication date

1 July 2009

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31 January 2017

published in

Journal of Cell Science

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31 January 2017

volume

122

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31 January 2017

issue

Pt 13

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31 January 2017

page(s)

2274–2282

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Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin

31 January 2017

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Novel association of Vav2 and Nek3 modulates signaling through the human prolactin receptor

17 March 2017

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The Serine/Threonine Kinase Nek6 Is Required for Cell Cycle Progression through Mitosis

17 March 2017

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A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases

17 March 2017

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17 March 2017

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The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

17 March 2017

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In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

17 March 2017

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Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression

17 March 2017

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17 March 2017

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17 March 2017

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Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice

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Activity of the human centrosomal kinase, Nek2, depends on an unusual leucine zipper dimerization motif

17 March 2017

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A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.

17 March 2017

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Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans

17 March 2017

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Isolation of a novel protein kinase-encoding gene from yeast by oligodeoxyribonucleotide probing

17 March 2017

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Post-translational modifications regulate microtubule function

17 March 2017

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6 April 2017

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7 April 2017

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Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

7 April 2017

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7 April 2017

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7 April 2017

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29 September 2017

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The mammalian Nek1 kinase is involved in primary cilium formation

29 September 2017

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Phylogenetic analysis of the Neks reveals early diversification of ciliary-cell cycle kinases

29 September 2017

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Nek2 as an effective target for inhibition of tumorigenic growth and peritoneal dissemination of cholangiocarcinoma

29 September 2017

1 reference

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Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation

29 September 2017

1 reference

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Nek3 kinase regulates prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

Is there any association between nek3 and cancers with frequent 13q14 deletion?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

Characterization of a poplar NIMA-related kinase PNek1 and its potential role in meristematic activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

29 September 2017

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Identification and sequence analysis of six new members of the NIMA-related kinase family in Chlamydomonas

29 September 2017

1 reference

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Never say never. The NIMA-related protein kinases in mitotic control

29 September 2017

1 reference

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Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

The FA2 gene of Chlamydomonas encodes a NIMA family kinase with roles in cell cycle progression and microtubule severing during deflagellation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

Cloning and characterization of the murine Nek3 protein kinase, a novel member of the NIMA family of putative cell cycle regulators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

Genetics of the deflagellation pathway in Chlamydomonas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

Characterization of mammalian NIMA-related kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

Cell cycle. The NIMA kinase joins forces with Cdc2.

29 September 2017

1 reference

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Premature chromatin condensation upon accumulation of NIMA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

Posttranslational modification and microtubule stability

29 September 2017

1 reference

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PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity

29 September 2017

1 reference

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Identification of CfNek, a novel member of the NIMA family of cell cycle regulators, as a polypeptide copurifying with tubulin polyglutamylation activity in Crithidia

29 September 2017

1 reference

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Fa1p is a 171 kDa protein essential for axonemal microtubule severing in Chlamydomonas.

3 June 2018

1 reference

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Properties and regulation of the cell cycle-specific NIMA protein kinase of Aspergillus nidulans.

3 June 2018

1 reference

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Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homolog of the mitotic regulator NIMA of Aspergillus nidulans.

3 June 2018

1 reference

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Acetylated and detyrosinated alpha-tubulins are co-localized in stable microtubules in rat meningeal fibroblasts

3 June 2018

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N-acetyltransferase ARD1-NAT1 regulates neuronal dendritic development.

3 June 2018

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27 November 2018

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Armadillo repeat-containing kinesins and a NIMA-related kinase are required for epidermal-cell morphogenesis in Arabidopsis.

27 November 2018

1 reference

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Members of the plant NIMA-related kinases are involved in organ development and vascularization in poplar, Arabidopsis and rice

27 November 2018

1 reference

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NEK7 is a centrosomal kinase critical for microtubule nucleation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

27 November 2018

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Drosophila Nek2 protein kinase knockdown leads to centrosome maturation defects while overexpression causes centrosome fragmentation and cytokinesis failure.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2723145

DdNek2, the first non-vertebrate homologue of human Nek2, is involved in the formation of microtubule-organizing centers.

27 November 2018

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27 November 2018

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27 November 2018

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A NIMA homologue promotes chromatin condensation in fission yeast.

27 November 2018

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HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions

27 November 2018

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12 December 2020

Altered expression of prolactin receptor-associated signaling proteins in human breast carcinoma

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12 December 2020

A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice

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12 December 2020

Identifiers

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31 January 2017

0 references

1 reference