A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases (Q24306818)

GOA release 2020-03-11

NIMA related kinase 7

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GOA release 2020-03-11

protein phosphorylation

1 reference

GOA release 2020-03-11

Joan Roig

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Bruce E Kemp

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Christopher Belham

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Jennifer A Caldwell

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Yumi Aoyama

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Michael Comb

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Joseph Avruch

Journal of Biological Chemistry

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language of work or name

English

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publication date

12 September 2003

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published in

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volume

278

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issue

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page(s)

34897-909

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cites work

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Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression

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Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses

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Never say never. The NIMA-related protein kinases in mitotic control

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Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice

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A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish

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Identification of the NIMA family kinases NEK6/7 as regulators of the p70 ribosomal S6 kinase

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Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivo

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Insulin activates a 70-kDa S6 kinase through serine/threonine-specific phosphorylation of the enzyme polypeptide

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Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II.

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Autophosphorylation induces autoactivation and a decrease in the Src homology 2 domain accessibility of the Lyn protein kinase.

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The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclin B: coordination of two mitosis promoting kinases.

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A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel

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Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

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Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans

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Characterization of pp60c-src Tyrosine Kinase Activities Using a Continuous Assay: Autoactivation of the Enzyme Is an Intermolecular Autophosphorylation Process

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Mitotic phosphorylation of DNA topoisomerase II alpha by protein kinase CK2 creates the MPM-2 phosphoepitope on Ser-1469

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7 January 2021