The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase (Q24296836)

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1 November 2019

title

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase (English)

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1 November 2019

1 reference

GOA release 2020-03-11

Histone deacetylase 6

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tubulin deacetylase activity

GOA release 2020-03-11

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GOA release 2020-03-11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620231%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Brian J North

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1 November 2019

Brett L Marshall

series ordinal

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1 November 2019

Margie T Borra

series ordinal

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1 November 2019

John M Denu

series ordinal

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1 November 2019

language of work or name

English

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publication date

1 February 2003

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1 November 2019

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1 November 2019

volume

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1 November 2019

issue

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1 November 2019

page(s)

437-444

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Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2

1 November 2019

cites work

1 reference

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7 January 2021

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

1 reference

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7 January 2021

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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7 January 2021

Herpes simplex virus type 1 tegument protein VP22 induces the stabilization and hyperacetylation of microtubules.

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7 January 2021

Characterization of a human RPD3 ortholog, HDAC3

1 reference

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7 January 2021

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900038-8

7 January 2021

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

1 reference

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7 January 2021

The molecular biology of the SIR proteins

1 reference

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7 January 2021

Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

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7 January 2021

Active erk regulates microtubule stability in H-ras-transformed cells

1 reference

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7 January 2021

HDAC6 is a microtubule-associated deacetylase

1 reference

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7 January 2021

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

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7 January 2021

Roles of histone acetyltransferases and deacetylases in gene regulation

1 reference

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7 January 2021

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

1 reference

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7 January 2021

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

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7 January 2021

Tubulin post-translational modifications--enzymes and their mechanisms of action

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7 January 2021

Structural insights into microtubule function

1 reference

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7 January 2021

High-resolution model of the microtubule

1 reference

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7 January 2021

A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast

1 reference

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7 January 2021

Microtubules containing acetylated alpha-tubulin in mammalian cells in culture

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7 January 2021

The diversity of acetylated proteins

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7 January 2021

The differential distribution of acetylated and detyrosinated alpha-tubulin in the microtubular cytoskeleton and primary cilia of hyaline cartilage chondrocytes.

1 reference

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7 January 2021

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900038-8

7 January 2021

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900038-8

7 January 2021

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900038-8

7 January 2021

10.1016/S1097-2765(03)00038-8

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620231%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12620231%20AND%20SRC:MED&resulttype=core&format=json