Farnesylation of Ras is important for the interaction with phosphoinositide 3-kinase gamma (Q28146104)

0 references

C Meyer

0 references

R Heinze

0 references

D Kadereit

0 references

R Wetzker

All ras proteins are polyisoprenylated but only some are palmitoylated

0 references

language of work or name

English

0 references

publication date

November 1999

0 references

published in

FEBS Journal

0 references

volume

266

0 references

issue

0 references

page(s)

70-82

0 references

cites work

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.1999.00815.X

Stimulation of gene induction and cell growth by the Ras effector Rlf

21 April 2017

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.1999.00815.X

Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras

21 April 2017

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.1999.00815.X

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 April 2017

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.1999.00815.X

The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

21 April 2017

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.1999.00815.X

Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 April 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

21 April 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation

21 April 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Activation of Raf as a result of recruitment to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

The Farnesyl Group of H-Ras Facilitates the Activation of a Soluble Upstream Activator of Mitogen-activated Protein Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Post-translational modification of H-Ras is required for activation of, but not for association with, B-Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Purification and characterization of REKS from Xenopus eggs. Identification of REKS as a Ras-dependent mitogen-activated protein kinase kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Gbetagamma stimulates phosphoinositide 3-kinase-gamma by direct interaction with two domains of the catalytic p110 subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Interaction of Ras with phosphoinositide 3-kinase gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Reticulocyte lysate assay for in vitro translation and posttranslational modification of Ras proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Ras-Raf complexes: analyses of complexes formed in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Lipid kinase and protein kinase activities of G-protein-coupled phosphoinositide 3-kinase gamma: structure-activity analysis and interactions with wortmannin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Ras C-terminal processing enzymes--new drug targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Equilibrium and kinetic measurements reveal rapidly reversible binding of Ras to Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

The posttranslational processing of ras p21 is critical for its stimulation of yeast adenylate cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

The effect of posttranslational modifications on the interaction of Ras2 with adenylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X

Evidence for a High Affinity, Saturable, Prenylation-dependent p21 Binding Site in Plasma Membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00815.X