Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells (Q41546925)

3 October 2017

title

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells (English)

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3 October 2017

J L Goldstein

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3 October 2017

G L James

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3 October 2017

M S Brown

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3 October 2017

T E Rawson

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3 October 2017

T C Somers

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3 October 2017

R S McDowell

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3 October 2017

C W Crowley

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3 October 2017

B K Lucas

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3 October 2017

A D Levinson

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3 October 2017

J C Marsters

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3 October 2017

language of work or name

English

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publication date

1 June 1993

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3 October 2017

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3 October 2017

volume

260

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3 October 2017

issue

5116

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3 October 2017

page(s)

1937-1942

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Retinal degeneration in choroideremia: deficiency of rab geranylgeranyl transferase

3 October 2017

cites work

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11 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.8380507

Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Transient reversion of ras oncogene-induced cell transformation by antibodies specific for amino acid 12 of ras protein

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https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Farnesylcysteine, a constituent of the alpha and beta subunits of rabbit skeletal muscle phosphorylase kinase: localization by conversion to S-ethylcysteine and by tandem mass spectrometry

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

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11 October 2022

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Regulators and Effectors of ras Proteins

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Ras C-terminal processing enzymes--new drug targets?

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Enzymatic modification of proteins with a geranylgeranyl isoprenoid

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Steady-state kinetic mechanism of Ras farnesyl:protein transferase

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

p21ras is modified by a farnesyl isoprenoid

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Tetrapeptide inhibitors of protein farnesyltransferase: amino-terminal substitution in phenylalanine-containing tetrapeptides restores farnesylation

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Prenylated proteins: the structure of the isoprenoid group

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Posttranslational modification of proteins by isoprenoids in mammalian cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Identification of geranylgeranyl-modified proteins in HeLa cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Purification of component A of Rab geranylgeranyl transferase: possible identity with the choroideremia gene product

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Linearization of baculovirus DNA enhances the recovery of recombinant virus expression vectors

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Biological properties of human c-Ha-ras1 genes mutated at codon 12.

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Identification of Ras farnesyltransferase inhibitors by microbial screening

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

All ras proteins are polyisoprenylated but only some are palmitoylated

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

cDNA cloning and expression of the peptide-binding β subunit of rat p21rasfarnesyltransferase, the counterpart of yeast DPR1/RAM1

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Inhibition of farnesyl-protein transferase by gliotoxin and acetylgliotoxin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Pepticinnamins, new farnesyl-protein transferase inhibitors produced by an actinomycete. I. Producing strain, fermentation, isolation and biological activity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Cloning and expression of a cDNA encoding the alpha subunit of rat p21ras protein farnesyltransferase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Non-peptide ligands for peptide receptors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Requirement for c-ras proteins during viral oncogene transformation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Conformational constraints: nonpeptide beta-turn mimics

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Protein prenylation: genes, enzymes, targets, and functions.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Pepticinnamins, new farnesyl-protein transferase inhibitors produced by an actinomycete. II. Structural elucidation of pepticinnamin E

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.8316834

Identifiers

DOI

10.1126/SCIENCE.8316834

1 reference

3 October 2017

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