The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue (Q24323252)

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C Herrmann

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A Scherer

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F McCormick

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A Wittinghofer

The ins and outs of Raf kinases

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language of work or name

English

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publication date

15 June 1995

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published in

Nature

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volume

375

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issue

6532

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page(s)

554-60

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cites work

1 reference

7 January 2021

Regulation of Ras-mediated signalling: more than one way to skin a cat.

1 reference

7 January 2021

GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.

1 reference

7 January 2021

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

1 reference

7 January 2021

Complex formation between RAS and RAF and other protein kinases

1 reference

7 January 2021

Mammalian Ras interacts directly with the serine/threonine kinase Raf

1 reference

7 January 2021

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

1 reference

7 January 2021

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

1 reference

7 January 2021

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1 reference

7 January 2021

Activation of Raf as a result of recruitment to the plasma membrane

1 reference

7 January 2021

Chemical shift assignments and folding topology of the Ras-binding domain of human Raf-1 as determined by heteronuclear three-dimensional NMR spectroscopy.

1 reference

7 January 2021

Critical binding and regulatory interactions between Ras and Raf occur through a small, stable N-terminal domain of Raf and specific Ras effector residues

1 reference

7 January 2021

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

1 reference

7 January 2021

Inhibition of GTPase activating protein stimulation of Ras-p21 GTPase by the Krev-1 gene product

1 reference

7 January 2021

Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator

1 reference

7 January 2021

ralGDS family members interact with the effector loop of ras p21.

1 reference

7 January 2021

Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap

1 reference

7 January 2021

1 reference

7 January 2021

The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination

1 reference

7 January 2021

RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts

1 reference

7 January 2021

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

1 reference

7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

7 January 2021

Improved Fourier coefficients for maps using phases from partial structures with errors

1 reference

7 January 2021

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

7 January 2021

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

1 reference

7 January 2021

Structure of the human ADP-ribosylation factor 1 complexed with GDP

1 reference

7 January 2021

Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form.

1 reference

7 January 2021

The effector interactions of p21ras

1 reference

7 January 2021

Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis

1 reference

7 January 2021

Structure of ubiquitin refined at 1.8 A resolution

1 reference

7 January 2021

Protein superfamilies and domain superfolds

1 reference

7 January 2021

Analytical molecular surface calculation

1 reference

7 January 2021

Shape complementarity at protein/protein interfaces

1 reference

7 January 2021

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product.

1 reference

7 January 2021

A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function

1 reference

7 January 2021

Multiple Ras functions can contribute to mammalian cell transformation

1 reference

7 January 2021

Pharmaceutical research in molecular oncology

1 reference

7 January 2021

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1 reference

7 January 2021

AMoRe: an automated package for molecular replacement

1 reference

7 January 2021

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

1 reference

7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

7 January 2021