Comprehensive characterization of the Published Kinase Inhibitor Set (Q27702518)

From Wikidata

Jump to navigation Jump to search

scientific article

edit

Language	Label	Description	Also known as
English	Comprehensive characterization of the Published Kinase Inhibitor Set	scientific article

Statements

instance of

scholarly article

0 references

title

Comprehensive characterization of the Published Kinase Inhibitor Set (English)

0 references

author

Eidarus Salah

series ordinal

5

0 references

Eugene Muratov

series ordinal

13

0 references

Denis Fourches

series ordinal

12

0 references

John P. Overington

series ordinal

21

0 references

Ayman Al Haj Zen

object named as

Ayman Al Haj Zen

series ordinal

11

0 references

David Drewry

object named as

David H Drewry

series ordinal

26

0 references

Jonathan M Elkins

object named as

Jonathan M Elkins

series ordinal

1

0 references

Susanne Müller

object named as

Susanne Müller

series ordinal

23

0 references

Stefan Knapp

object named as

Stefan Knapp

series ordinal

27

0 references

Francis Atkinson

object named as

Francis L Atkinson

series ordinal

20

0 references

Bryan L. Roth

series ordinal

10

object named as

Bryan L Roth

0 references

Marta Szklarz

series ordinal

3

object named as

Marta Szklarz

0 references

Vita Fedele

series ordinal

2

object named as

Vita Fedele

0 references

Kamal R. Abdul Azeez

series ordinal

4

object named as

Kamal R Abdul Azeez

0 references

William J Zuercher

series ordinal

28

object named as

William J Zuercher

0 references

Timothy M Willson

series ordinal

25

object named as

Timothy M Willson

0 references

author name string

Jowita Mikolajczyk

series ordinal

6

0 references

Sergei Romanov

series ordinal

7

0 references

Nikolai Sepetov

series ordinal

8

0 references

Xi-Ping Huang

series ordinal

9

0 references

Alex Tropsha

series ordinal

14

0 references

Joel Morris

series ordinal

15

0 references

Beverly A Teicher

series ordinal

16

0 references

Mark Kunkel

series ordinal

17

0 references

Eric Polley

series ordinal

18

0 references

Karen E Lackey

series ordinal

19

0 references

Daniel J Price

series ordinal

24

0 references

publication date

January 2016

0 references

published in

Nature Biotechnology

0 references

volume

34

0 references

issue

1

0 references

page(s)

95-103

0 references

cites work

Open access chemical and clinical probes to support drug discovery

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

Discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

LOK is a novel mouse STE20-like protein kinase that is expressed predominantly in lymphocytes

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

The selectivity of protein kinase inhibitors: a further update

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

A quantitative analysis of kinase inhibitor selectivity

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine(2B) receptor agonists: implications for drug safety assessment

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

Structural Features for Functional Selectivity at Serotonin Receptors

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038/NBT.3374

retrieved

21 April 2017

Targeting cancer with small molecule kinase inhibitors

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNBT.3374

retrieved

21 April 2017

Global mapping of pharmacological space

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNBT.3374

retrieved

21 April 2017

The NCI60 human tumour cell line anticancer drug screen

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNBT.3374

retrieved

21 April 2017

Angiogenesis: an organizing principle for drug discovery?

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNBT.3374

retrieved

21 April 2017

VEGF receptor signalling - in control of vascular function

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNBT.3374

retrieved

21 April 2017

Comprehensive analysis of kinase inhibitor selectivity

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNBT.3374

retrieved

21 April 2017

A small molecule-kinase interaction map for clinical kinase inhibitors

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNBT.3374

retrieved

21 April 2017

Using Graph Indices for the Analysis and Comparison of Chemical Datasets

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FDA-approved small-molecule kinase inhibitors.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orally active 4-amino-5-diarylurea-furo[2,3-d]pyrimidine derivatives as anti-angiogenic agent inhibiting VEGFR2 and Tie-2

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis for sunitinib efficacy and future clinical development

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An information-intensive approach to the molecular pharmacology of cancer.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of chemical coverage of kinome space and its implications for kinase drug discovery.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinase inhibitor selectivity profiling using differential scanning fluorimetry

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro angiogenesis: endothelial cell tube formation on gelled basement membrane extract

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Automated design of ligands to polypharmacological profiles.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Navigating the kinome

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinase drug discovery--what's next in the field?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Coiled-Coil Enabled Split-Luciferase Three-Hybrid System: Applied Toward Profiling Inhibitors of Protein Kinases

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a cell-based, high-throughput screening assay for ATM kinase inhibitors.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

System-based drug discovery within the human kinome

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seeding collaborations to advance kinase science with the GSK Published Kinase Inhibitor Set (PKIS)

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trends in kinase selectivity: insights for target class-focused library screening

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The (un)targeted cancer kinome

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The purinome, a complex mix of drug and toxicity targets

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery and development of sorafenib: a multikinase inhibitor for treating cancer.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The identification of potent and selective imidazole-based inhibitors of B-Raf kinase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-aryl-pyrazolo[3,4-b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probing the probes: fitness factors for small molecule tools

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of cell-based RNAi screens.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Features of selective kinase inhibitors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CellMiner: a web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26501955

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NBT.3374

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2150197

Dimensions Publication ID

1024715377

0 references

OpenCitations bibliographic resource ID

2150197

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2150197

PubMed publication ID

26501955

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2150197

ResearchGate publication ID

283260001

0 references

 

Sitelinks

Wikipedia(0 entries)

edit

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27702518&oldid=2175344273"