Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine(2B) receptor agonists: implications for drug safety assessment (Q28250560)

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English	Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine(2B) receptor agonists: implications for drug safety assessment	scientific article

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Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine(2B) receptor agonists: implications for drug safety assessment (English)

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author name string

Xi-Ping Huang

1

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Vincent Setola

2

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Prem N Yadav

3

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John A Allen

4

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Sarah C Rogan

5

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Bonnie J Hanson

6

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Chetana Revankar

7

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Matt Robers

8

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Chris Doucette

9

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Bryan L Roth

10

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language of work or name

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publication date

October 2009

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Molecular Pharmacology

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76

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4

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710-22

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2769050/fullTextXML

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inferred from PubMed Central ID database lookup

5-hydroxytryptamine (5HT)-induced valvulopathy: compositional valvular alterations are associated with 5HT2B receptor and 5HT transporter transcript changes in Sprague-Dawley rats

1 reference

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Possible association between 3,4-methylenedioxymethamphetamine abuse and valvular heart disease

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Drugs and valvular heart disease

1 reference

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Functional Selectivity and Classical Concepts of Quantitative Pharmacology

1 reference

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Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor

1 reference

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3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro

1 reference

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1 reference

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Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine

1 reference

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Histologic changes in three explanted native cardiac valves following use of fenfluramines

1 reference

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Valvular heart disease associated with fenfluramine-phentermine

1 reference

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1 reference

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The expanded biology of serotonin

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1 reference

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Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization

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N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity

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Lorcaserin (APD356), a selective 5-HT(2C) agonist, reduces body weight in obese men and women

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5-Hydroxytryptamine (5HT) receptors in the heart valves of cynomolgus monkeys and Sprague-Dawley rats

1 reference

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27 November 2018

Identifiers

10.1124/MOL.109.058057

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