Structure of an integrin IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation (Q27657684)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

main subject

transmembrane protein

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jun Yang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Yan-Qing Ma

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Edward F Plow

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

1 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

9 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

106

1 reference

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9 February 2020

issue

1 reference

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9 February 2020

page(s)

17729-17734

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling

9 February 2020

cites work

1 reference

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20 March 2017

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Migfilin, a molecular switch in regulation of integrin activation

20 March 2017

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NMR solution conformations and interactions of integrin alphaLbeta2 cytoplasmic tails

20 March 2017

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Structure of the Integrin IIb Transmembrane Segment

20 March 2017

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Coiled-Coil Irregularities and Instabilities in Group A Streptococcus M1 Are Required for Virulence

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20 March 2017

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Structural basis of integrin activation by talin

20 March 2017

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A specific interface between integrin transmembrane helices and affinity for ligand

20 March 2017

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20 March 2017

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A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

20 March 2017

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Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits

20 March 2017

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Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains

20 March 2017

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Integrins: bidirectional, allosteric signaling machines

20 March 2017

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20 March 2017

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Molecular basis of CIB binding to the integrin alpha IIb cytoplasmic domain

22 April 2017

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Multiple approaches converge on the structure of the integrin alphaIIb/beta3 transmembrane heterodimer

20 March 2017

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Interactions of platelet integrin alphaIIb and beta3 transmembrane domains in mammalian cell membranes and their role in integrin activation

29 September 2017

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De novo protein structure generation from incomplete chemical shift assignments.

29 September 2017

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Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment.

29 September 2017

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Evidence for a differential functional regulation of the two beta(3)-integrins alpha(V)beta(3) and alpha(IIb)beta(3).

29 September 2017

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CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbbeta3 activation

29 September 2017

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The structure of alpha-helical coiled coils

29 September 2017

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Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

29 September 2017

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A push-pull mechanism for regulating integrin function

29 September 2017

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Membrane-mediated structural transitions at the cytoplasmic face during integrin activation

29 September 2017

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Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography

29 September 2017

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NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution

29 September 2017

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29 September 2017

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Structural basis for the autoinhibition of talin in regulating integrin activation

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2 June 2018

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2 June 2018

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2 June 2018

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Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state

21 January 2018

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A coiled-coil structure of the alphaIIbbeta3 integrin transmembrane and cytoplasmic domains in its resting state

21 January 2018

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Cooperative role of the membrane-proximal and -distal residues of the integrin beta3 cytoplasmic domain in regulation of talin-mediated alpha IIb beta3 activation

21 January 2018

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21 January 2018

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Regulation of Integrin αIIbβ3Activation by Distinct Regions of Its Cytoplasmic Tails†

21 January 2018

1 reference

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Unambiguous prediction of human integrin transmembrane heterodimer interactions using only homologous sequences

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19805198

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dynamic helix interactions in transmembrane signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19805198

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19805198

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0909589106

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

ADS bibcode

2009PNAS..10617729Y

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

19805198

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json