Structure of an integrin IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation (Q27657684)

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Language	Label	Description	Also known as
English	Structure of an integrin IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation	scientific article

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

transmembrane protein

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3

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9 February 2020

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Jun Yang

1

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9 February 2020

Yan-Qing Ma

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Edward F Plow

5

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9 February 2020

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publication date

1 October 2009

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9 February 2020

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

106

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

42

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

17729-17734

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Migfilin, a molecular switch in regulation of integrin activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

NMR solution conformations and interactions of integrin alphaLbeta2 cytoplasmic tails

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Structure of the Integrin IIb Transmembrane Segment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Coiled-Coil Irregularities and Instabilities in Group A Streptococcus M1 Are Required for Virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Structural basis of integrin activation by talin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

A specific interface between integrin transmembrane helices and affinity for ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Involvement of transmembrane domain interactions in signal transduction by alpha/beta integrins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Integrins: bidirectional, allosteric signaling machines

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

https://api.crossref.org/works/10.1073%2FPNAS.0909589106

22 April 2017

Molecular basis of CIB binding to the integrin alpha IIb cytoplasmic domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

20 March 2017

Multiple approaches converge on the structure of the integrin alphaIIb/beta3 transmembrane heterodimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

Interactions of platelet integrin alphaIIb and beta3 transmembrane domains in mammalian cell membranes and their role in integrin activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

De novo protein structure generation from incomplete chemical shift assignments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

Evidence for a differential functional regulation of the two beta(3)-integrins alpha(V)beta(3) and alpha(IIb)beta(3).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbbeta3 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

The structure of alpha-helical coiled coils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

A push-pull mechanism for regulating integrin function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

Membrane-mediated structural transitions at the cytoplasmic face during integrin activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

29 September 2017

The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

2 June 2018

Structural basis for the autoinhibition of talin in regulating integrin activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

2 June 2018

The molecular basis of filamin binding to integrins and competition with talin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

2 June 2018

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764936

2 June 2018

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909589106

21 January 2018

Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909589106

21 January 2018

A coiled-coil structure of the alphaIIbbeta3 integrin transmembrane and cytoplasmic domains in its resting state

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909589106

21 January 2018

Cooperative role of the membrane-proximal and -distal residues of the integrin beta3 cytoplasmic domain in regulation of talin-mediated alpha IIb beta3 activation

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909589106

21 January 2018

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909589106

21 January 2018

Regulation of Integrin αIIbβ3Activation by Distinct Regions of Its Cytoplasmic Tails†

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909589106

21 January 2018

Unambiguous prediction of human integrin transmembrane heterodimer interactions using only homologous sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/19805198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic helix interactions in transmembrane signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19805198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18

1 reference

https://pubmed.ncbi.nlm.nih.gov/19805198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0909589106

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

2009PNAS..10617729Y

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19805198%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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