SIRT1 and SIRT2: emerging targets in neurodegeneration (Q26864929)

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24 February 2020

review article

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title

SIRT1 and SIRT2: emerging targets in neurodegeneration (English)

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24 February 2020

4 references

25 April 2019

12 September 2019

28 September 2019

12 October 2019

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12 September 2019

1 reference

28 September 2019

1 reference

12 October 2019

Tiago Fleming Outeiro

series ordinal

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24 February 2020

Gizem Donmez

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24 February 2020

language of work or name

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18 February 2013

1 reference

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24 February 2020

published in

EMBO Molecular Medicine

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28 September 2019

12 October 2019

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24 February 2020

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24 February 2020

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24 February 2020

page(s)

344-352

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Creative Commons Attribution 2.5 Generic

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SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis

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7 April 2017

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7 April 2017

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Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein

7 April 2017

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Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity

28 September 2017

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SIRT1 protects against α-synuclein aggregation by activating molecular chaperones

28 September 2017

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Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway

28 September 2017

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28 September 2017

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Aging and disease: connections to sirtuins

28 September 2017

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28 September 2017

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The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide.

28 September 2017

1 reference

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From heterochromatin islands to the NAD World: a hierarchical view of aging through the functions of mammalian Sirt1 and systemic NAD biosynthesis

28 September 2017

1 reference

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Brain SIRT1: anatomical distribution and regulation by energy availability

28 September 2017

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The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration

28 September 2017

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Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease.

28 September 2017

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Genetic links between diet and lifespan: shared mechanisms from yeast to humans

28 September 2017

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28 September 2017

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31 May 2018

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31 May 2018

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SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

21 January 2018

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Reversal of Behavioral and Metabolic Abnormalities, and Insulin Resistance Syndrome, by Dietary Restriction in Mice Deficient in Brain-Derived Neurotrophic Factor

21 January 2018

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21 January 2018

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SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons

21 January 2018

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Sirt1 contributes critically to the redox-dependent fate of neural progenitors.

21 January 2018

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NF-kappaB signaling in the aging process

21 January 2018

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Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation.

21 January 2018

1 reference

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Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus).

21 January 2018

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An intervention resembling caloric restriction prolongs life span and retards aging in yeast

28 November 2018

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12 December 2020

Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence

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12 December 2020

The logic linking protein acetylation and metabolism

1 reference

12 December 2020

Accumulation of human alpha-synuclein in different cytoskeletons in Lewy bodies in brains of dementia with Lewy bodies

1 reference

12 December 2020

Mixed results for dieting monkeys

1 reference

12 December 2020

Pathogenesis of axonal degeneration: parallels between Wallerian degeneration and vincristine neuropathy

1 reference

12 December 2020

Life extension by dietary restriction in the bowl and doily spider, Frontinella pyramitela

1 reference

12 December 2020

Clinical and pathological features of a parkinsonian syndrome in a family with an Ala53Thr ?-synuclein mutation

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1002/EMMM.201302451

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23417962%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23417962%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

23417962

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23417962%20AND%20SRC:MED&resulttype=core&format=json