Understanding platelet generation from megakaryocytes: implications for in vitro-derived platelets (Q26770860)

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English	Understanding platelet generation from megakaryocytes: implications for in vitro-derived platelets	scientific article

Statements

instance of

scholarly article

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title

Understanding platelet generation from megakaryocytes: implications for in vitro-derived platelets (English)

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main subject

cell biology

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author name string

Xiuli Sim

series ordinal

1

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Mortimer Poncz

series ordinal

2

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Paul Gadue

series ordinal

3

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Deborah L French

series ordinal

4

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language of work or name

English

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publication date

10 March 2016

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published in

Blood

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volume

127

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issue

10

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page(s)

1227-33

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cites work

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Platelet demand modulates the type of intravascular protrusion of megakaryocytes in bone marrow

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SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury

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Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation

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Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways

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Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells

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Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

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28 September 2017

Infusion of mature megakaryocytes into mice yields functional platelets

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Platelet formation

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28 September 2017

In vitro megakaryocyte production and platelet biogenesis: state of the art

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28 September 2017

Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells

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28 September 2017

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28 September 2017

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28 September 2017

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The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis

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Megakaryocyte development and platelet production.

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28 September 2017

Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis

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28 September 2017

Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets

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28 September 2017

Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation

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28 September 2017

Megakaryocytic progenitors can be generated ex vivo and safely administered to autologous peripheral blood progenitor cell transplant recipients.

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28 September 2017

Platelets generated in vitro from proplatelet-displaying human megakaryocytes are functional

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28 September 2017

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31 May 2018

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31 May 2018

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31 May 2018

Scalable generation of universal platelets from human induced pluripotent stem cells.

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28 November 2018

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28 November 2018

Developmental changes in human megakaryopoiesis.

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28 November 2018

Mcl-1 and Bcl-xL coordinately regulate megakaryocyte survival

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28 November 2018

Closure times measured by the platelet function analyzer PFA-100 are longer in neonatal blood compared to cord blood samples

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786833

retrieved

28 November 2018

Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786833

retrieved

28 November 2018

Mitochondrial control of platelet apoptosis: effect of cyclosporin A, an inhibitor of the mitochondrial permeability transition pore

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786833

retrieved

28 November 2018

Bcl-2 family proteins are essential for platelet survival.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786833

retrieved

28 November 2018

GPVI down-regulation in murine platelets through metalloproteinase-dependent shedding

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786833

retrieved

28 November 2018

Evidence for the presence of murine primitive megakaryocytopoiesis in the early yolk sac.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786833

retrieved

28 November 2018

Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786833

retrieved

28 November 2018

Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26787738

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet glycocalicin. Its membrane association and solubilization in aqueous media

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26787738

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies with a murine monoclonal antibody that abolishes ristocetin-induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26787738

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Markedly reduced expression of platelet c-mpl receptor in essential thrombocythemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26787738

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet c-mpl expression is dysregulated in patients with essential thrombocythaemia but this is not of diagnostic value

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26787738

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet transfusions

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26787738

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic Visualization of Thrombopoiesis Within Bone Marrow

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/26787738

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Markedly Reduced Expression of Platelet c-mpl Receptor in Essential Thrombocythemia

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1182%2FBLOOD-2015-08-607929

retrieved

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

DOI

10.1182/BLOOD-2015-08-607929

0 references

PMC publication ID

4786833

0 references

PubMed publication ID

26787738

0 references

 

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