Actin inhibition increases megakaryocyte proplatelet formation through an apoptosis-dependent mechanism (Q35416666)

8 August 2017

title

Actin inhibition increases megakaryocyte proplatelet formation through an apoptosis-dependent mechanism (English)

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8 August 2017

Mauro P Avanzi

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8 August 2017

Marina Izak

series ordinal

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8 August 2017

Oluwasijibomi E Oluwadara

series ordinal

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8 August 2017

William Beau Mitchell

series ordinal

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8 August 2017

language of work or name

English

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publication date

14 April 2015

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8 August 2017

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8 August 2017

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8 August 2017

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8 August 2017

page(s)

e0125057

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Creative Commons Attribution 4.0 International

8 August 2017

start time

14 April 2015

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways

1 reference

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RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation

12 July 2018

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The incredible journey: From megakaryocyte development to platelet formation.

12 July 2018

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Platelets: production, morphology and ultrastructure

12 July 2018

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Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function

12 July 2018

1 reference

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Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

12 July 2018

1 reference

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Cytoskeletal mechanics of proplatelet maturation and platelet release.

12 July 2018

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Mitochondria and cell death: outer membrane permeabilization and beyond

12 July 2018

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Contributions of TRAIL-mediated megakaryocyte apoptosis to impaired megakaryocyte and platelet production in immune thrombocytopenia

12 July 2018

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Apoptotic processes in megakaryocytes and platelets

12 July 2018

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Latrunculin a has a strong anticancer effect in a peritoneal dissemination model of human gastric cancer in mice

12 July 2018

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Caspase activation is involved in early megakaryocyte differentiation but not in platelet production from megakaryocytes

12 July 2018

1 reference

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12 July 2018

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Continuous expression of Bcl-xL protein during megakaryopoiesis is post-translationally regulated by thrombopoietin-mediated Akt activation, which prevents the cleavage of Bcl-xL.

12 July 2018

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Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

12 July 2018

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Bid, a BH3-only multi-functional molecule, is at the cross road of life and death

12 July 2018

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Cell death independent of caspases: a review.

12 July 2018

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Role of apoptotic processes in platelet biogenesis

12 July 2018

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Bcl-2-family proteins and the role of mitochondria in apoptosis

12 July 2018

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Mitochondria: releasing power for life and unleashing the machineries of death

12 July 2018

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Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death

12 July 2018

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BclxL overexpression in megakaryocytes leads to impaired platelet fragmentation

12 July 2018

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Death and anti-death: tumour resistance to apoptosis

12 July 2018

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Induction of platelet formation from megakaryocytoid cells by nitric oxide

12 July 2018

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Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2.

12 July 2018

1 reference

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Antiapoptotic protein Bcl-x(L) is up-regulated during megakaryocytic differentiation of CD34(+) progenitors but is absent from senescent megakaryocytes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397066

The biochemistry of apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397066

Nitric oxide induces apoptosis in megakaryocytic cell lines.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397066

Bim: a novel member of the Bcl-2 family that promotes apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397066

Adhesive receptors, extracellular proteins and myosin IIA orchestrate proplatelet formation by human megakaryocytes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397066

Platelet formation is the consequence of caspase activation within megakaryocytes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397066

Gene expression profiling of normal and malignant CD34-derived megakaryocytic cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397066

Ultrastructural characterization of maturation, platelet release, and senescence of human cultured megakaryocytes

26 September 2018

1 reference

12 December 2020

Exposure of human megakaryocytes to high shear rates accelerates platelet production

1 reference

12 December 2020

Rho kinase inhibition drives megakaryocyte polyploidization and proplatelet formation through MYC and NFE2 downregulation

1 reference

12 December 2020

Fate of senescent megakaryocytes in the bone marrow

1 reference

12 December 2020

Modulation of apoptosis-associated genes bcl-2, bcl-x, and bax during rat liver regeneration

1 reference

12 December 2020

In vitro senescence and apoptotic cell death of human megakaryocytes

1 reference

12 December 2020

Bcl-x is a regulatory factor of apoptosis and differentiation in megakaryocytic lineage cells

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0125057

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DOI

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8 August 2017

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8 August 2017

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