SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury (Q33414625)

24735964

26 July 2017

title

SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury (English)

1 reference

26 July 2017

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24735964%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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13 June 2020

Katherine H Fegan

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13 June 2020

Paul D Kingsley

series ordinal

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13 June 2020

Kathleen E McGrath

series ordinal

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13 June 2020

language of work or name

English

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publication date

15 April 2014

1 reference

26 July 2017

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inferred from page(s)

published in

Blood

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13 June 2020

volume

124

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13 June 2020

issue

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13 June 2020

page(s)

277-286

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Improved quantitative analysis of primary bone marrow megakaryocytes utilizing imaging flow cytometry

13 June 2020

cites work

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EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress

14 July 2018

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14 July 2018

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14 July 2018

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Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression

14 July 2018

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Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

14 July 2018

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Low-dose radiation augments vasculogenesis signaling through HIF-1-dependent and -independent SDF-1 induction.

14 July 2018

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Bone marrow osteoblastic niche: a new model to study physiological regulation of megakaryopoiesis

14 July 2018

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Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation.

14 July 2018

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Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction.

14 July 2018

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Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells

14 July 2018

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Relationships between glycosaminoglycan and receptor binding sites in chemokines-the CXCL12 example.

14 July 2018

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Pathophysiological principles underlying the blood cell concentration responses used to assess the severity of effect after accidental whole-body radiation exposure: an essential basis for an evidence-based clinical triage

14 July 2018

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Phase 1 clinical study of eltrombopag, an oral, nonpeptide thrombopoietin receptor agonist

14 July 2018

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A novel role for PECAM-1 in megakaryocytokinesis and recovery of platelet counts in thrombocytopenic mice

14 July 2018

1 reference

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Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches

14 July 2018

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Regulation of CXCR4 signaling

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093683

Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma

14 July 2018

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Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3.

14 July 2018

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Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NF-kappaB activation

14 July 2018

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The bone marrow vascular niche: home of HSC differentiation and mobilization

14 July 2018

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In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment

14 July 2018

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Tie2 activation contributes to hemangiogenic regeneration after myelosuppression

14 July 2018

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

14 July 2018

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Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis

14 July 2018

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A direct measurement of the radiation sensitivity of normal mouse bone marrow cells

14 July 2018

1 reference

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Dipeptidyl peptidase IV (CD26) activity in the hematopoietic system: differences between the membrane-anchored and the released enzyme activity

14 July 2018

1 reference

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Hematologic consequences of exposure to ionizing radiation

14 July 2018

1 reference

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Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093683

Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093683

Stromal-derived factor 1-induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093683

Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093683

Binding of stromal derived factor-1alpha (SDF-1alpha) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets induces phosphorylation of mitogen-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/t

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093683

Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4093683

Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4.

14 July 2018

1 reference

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Megakaryocyte precursors, megakaryocytes and platelets express the HIV co-receptor CXCR4 on their surface: determination of response to stromal-derived factor-1 by megakaryocytes and platelets

14 July 2018

1 reference

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Phenotypic and functional evidence for the expression of CXCR4 receptor during megakaryocytopoiesis

14 July 2018

1 reference

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Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation

14 July 2018

1 reference

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Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.

14 July 2018

1 reference

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Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

14 July 2018

1 reference

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Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand.

14 July 2018

1 reference

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The megakaryocyte DNA content and platelet formation after the sublethal whole body irradiation of rats

14 July 2018

1 reference

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An electron microscope study of the rat megacaryocyte. II. Some aspects of platelet release and microtubules

14 July 2018

1 reference

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Stimulation of thrombocytopoiesis in irradiated mice.

14 July 2018

1 reference

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Localization of megakaryocytes in the bone marrow

14 July 2018

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Are diprotin A (Ile-Pro-Ile) and diprotin B (Val-Pro-Leu) inhibitors or substrates of dipeptidyl peptidase IV?

14 July 2018

1 reference

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Growth of mouse megakaryocyte colonies in vitro

14 July 2018

1 reference

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Regulation of proliferation of murine megakaryocyte progenitor cells by cell cycle

14 July 2018

1 reference

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IGF-1-mediated osteoblastic niche expansion enhances long-term hematopoietic stem cell engraftment after murine bone marrow transplantation.

14 July 2018

1 reference

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CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

31 October 2018

1 reference

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In vivo expansion of the megakaryocyte progenitor cell population in adult CD26-deficient mice

31 October 2018

1 reference

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Hypercholesterolemia promotes bone marrow cell mobilization by perturbing the SDF-1:CXCR4 axis

31 October 2018

1 reference

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Adhesive receptors, extracellular proteins and myosin IIA orchestrate proplatelet formation by human megakaryocytes.

31 October 2018

1 reference

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Diprotin A infusion into nonobese diabetic/severe combined immunodeficiency mice markedly enhances engraftment of human mobilized CD34+ peripheral blood cells

31 October 2018

1 reference

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Analysis of hematopoietic progenitors in the mouse embryo

31 October 2018

1 reference

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Increased plasma levels of stromal-derived factor-1 (SDF-1/CXCL12) enhance human thrombopoiesis and mobilize human colony-forming cells (CFC) in NOD/SCID mice

31 October 2018

1 reference

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Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ progenitor cells

31 October 2018

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The alpha-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion

31 October 2018

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A single injection of pegylated murine megakaryocyte growth and development factor (MGDF) into mice is sufficient to produce a profound stimulation of megakaryocyte frequency, size, and ploidization.

31 October 2018

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Differential gene expression during early murine yolk sac development.

31 October 2018

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Dual stem cell therapy after myocardial infarction acts specifically by enhanced homing via the SDF-1/CXCR4 axis

31 October 2018

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12 December 2020

Stromal cell-derived factor-1 (SDF-1) acts together with thrombopoietin to enhance the development of megakaryocytic progenitor cells (CFU-MK)

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12 December 2020

Fate of senescent megakaryocytes in the bone marrow

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12 December 2020

Modulation of megakaryocytopoiesis by thrombopoietin: the c-Mpl ligand

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12 December 2020

Restoration of the human stem cell niche after stem cell transplantation

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12 December 2020

In vivo biotinylation studies: specificity of labelling of reticulated platelets by thiazole orange and mepacrine

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12 December 2020

Parasinusoidal location of megakaryocytes in marrow: a determinant of platelet release

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12 December 2020

Human CD34(+)CXCR4(-) sorted cells harbor intracellular CXCR4, which can be functionally expressed and provide NOD/SCID repopulation

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12 December 2020

Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells

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12 December 2020

Effects of Radiation on the Thrombocytopoietic System of Mice

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12 December 2020

Isolation and characterization of human bone marrow microvascular endothelial cells: hematopoietic progenitor cell adhesion

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12 December 2020

The relationship between bone, hemopoietic stem cells, and vasculature

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12 December 2020

Ultrastructural and morphometric alterations in bone marrow stromal tissue after 7 Gy irradiation

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12 December 2020

VEGFR1 stimulates a CXCR4-dependent translocation of megakaryocytes to the vascular niche, enhancing platelet production in mice

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12 December 2020

Higher pH promotes megakaryocytic maturation and apoptosis

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12 December 2020

Dynamic Visualization of Thrombopoiesis Within Bone Marrow

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12 December 2020

Kinetic-microarchitectural correlations in the bone marrow of the mouse

1 reference

12 December 2020

A single dose of thrombopoietin shortly after myelosuppressive total body irradiation prevents pancytopenia in mice by promoting short-term multilineage spleen-repopulating cells at the transient expense of bone marrow-repopulating cells

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12 December 2020

Diprotins A and B, inhibitors of dipeptidyl aminopeptidase IV, produced by bacteria

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12 December 2020

Polyploidy and maturation of rat megakaryocytes

1 reference

12 December 2020

Differential regulation of actin stress fiber assembly and proplatelet formation by alpha2beta1 integrin and GPVI in human megakaryocytes

1 reference

12 December 2020

Stromal cell-derived factor 1alpha increases polyploidization of megakaryocytes generated by human hematopoietic progenitor cells

1 reference

12 December 2020

Pharmacodynamics and pharmacokinetics of AMG 531, a novel thrombopoietin receptor ligand

1 reference

12 December 2020

10.1182/BLOOD-2014-01-547638

Identifiers

DOI

1 reference

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13 June 2020

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13 June 2020

24735964

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