Akt-and CREB-mediated prostate cancer cell proliferation inhibition by Nexrutine, a Phellodendron amurense extract (Q24676177)

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Shylesh Bhaskaran

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Ashima Gupta

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Natasha Kyprianou

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Addanki P Kumar

Transcriptional regulation by the phosphorylation-dependent factor CREB

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language of work or name

English

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publication date

June 2006

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523-33

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cites work

1 reference

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The role of protein kinase A pathway and cAMP responsive element-binding protein in androgen receptor-mediated transcription at the prostate-specific antigen locus

7 April 2017

1 reference

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Cell death: critical control points

7 April 2017

1 reference

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The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

7 April 2017

1 reference

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CREB is a regulatory target for the protein kinase Akt/PKB

7 April 2017

1 reference

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Severe impairment of spermatogenesis in mice lacking the CREM gene

7 April 2017

1 reference

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

7 April 2017

1 reference

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Cellular survival: a play in three Akts

7 April 2017

1 reference

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Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey

7 April 2017

1 reference

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7 April 2017

Cancer statistics, 2004

1 reference

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Cancer chemoprevention with dietary phytochemicals

7 April 2017

1 reference

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2-Methoxyestradiol inhibits prostate tumor development in transgenic adenocarcinoma of mouse prostate: role of tumor necrosis factor-alpha-stimulated gene 6.

7 April 2017

1 reference

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Tomato products, lycopene, and prostate cancer: a review of the epidemiological literature

28 September 2017

1 reference

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Inhibition of the Akt, cyclooxygenase-2, and matrix metalloproteinase-9 pathways in combination with androgen deprivation therapy: potential therapeutic approaches for prostate cancer.

28 September 2017

1 reference

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Signaling intricacies take center stage in cancer cells

28 September 2017

1 reference

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The emerging role of the PI3-K-Akt pathway in prostate cancer progression

28 September 2017

1 reference

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Eugenol causes melanoma growth suppression through inhibition of E2F1 transcriptional activity

28 September 2017

1 reference

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Apoptotic regulators in prostatic intraepithelial neoplasia (PIN): value in prostate cancer detection and prevention

28 September 2017

1 reference

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Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer.

28 September 2017

1 reference

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Estrogens and anti-estrogens: key mediators of prostate carcinogenesis and new therapeutic candidates

28 September 2017

1 reference

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Unconventional therapy for prostate cancer: good, bad or questionable?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

4-Hydroxy-3-methoxybenzoic acid methyl ester: a curcumin derivative targets Akt/NF kappa B cell survival signaling pathway: potential for prostate cancer management

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Botanicals in cancer chemoprevention

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Principle of the bark of Phellodendron amurense to suppress the cellular immune response: effect of phellodendrine on cellular and humoral immune responses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Vegetables, fruits, legumes and prostate cancer: a multiethnic case-control study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Transcriptional regulation by cyclic AMP

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Mitochondria and the Bcl-2 family proteins in apoptosis signaling pathways

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

2-Methoxyestradiol interferes with NF kappa B transcriptional activity in primitive neuroectodermal brain tumors: implications for management

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

PC-SPES--a lesson for future dietary supplement research

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

2-methoxyestradiol blocks cell-cycle progression at G(2)/M phase and inhibits growth of human prostate cancer cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601469

bcl-2 over-expression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16820098

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fruit and vegetable intakes and prostate cancer risk

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16820098

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1593/NEO.05745

1 reference

1 reference

1 reference

PubMed publication ID

16820098

1 reference