2-methoxyestradiol blocks cell-cycle progression at G(2)/M phase and inhibits growth of human prostate cancer cells (Q43692320)

25 November 2017

title

2-methoxyestradiol blocks cell-cycle progression at G(2)/M phase and inhibits growth of human prostate cancer cells (English)

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25 November 2017

Kumar AP

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25 November 2017

Garcia GE

series ordinal

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25 November 2017

Slaga TJ

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25 November 2017

publication date

1 July 2001

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25 November 2017

published in

Molecular Carcinogenesis

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25 November 2017

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25 November 2017

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25 November 2017

page(s)

111-124

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25 November 2017

cites work

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The mammalian metabolite, 2-methoxyestradiol, affects P53 levels and apoptosis induction in transformed cells but not in normal cells

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Superinduction of wild-type p53 protein after 2-methoxyestradiol treatment of Ad5p53-transduced cells induces tumor cell apoptosis

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The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Regulation of rat ornithine decarboxylase promoter activity by binding of transcription factor Sp1.

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Transcription factor Sp3 antagonizes activation of the ornithine decarboxylase promoter by Sp1.

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Inhibition of the catechol-O-methyltransferase-catalyzed O-methylation of 2- and 4-hydroxyestradiol by catecholamine: implications for the mechanism of estrogen-induced carcinogenesis.

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Morphological and biochemical characterization and analysis of apoptosis

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Caspase structure, proteolytic substrates, and function during apoptotic cell death

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Principles of CDK regulation

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Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

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Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase

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Universal control mechanism regulating onset of M-phase

21 January 2018

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Regulation of p53 downstream genes.

21 January 2018

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Involvement of p21 in the PKC-induced regulation of the G2/M cell cycle transition

21 January 2018

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p53, the cellular gatekeeper for growth and division

21 January 2018

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p53 oncogene mutations in three human prostate cancer cell lines

21 January 2018

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p53-independent induction of p21 (WAF1/CIP1), reduction of cyclin B1 and G2/M arrest by the isoflavone genistein in human prostate carcinoma cells.

21 January 2018

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Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

21 January 2018

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Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site

21 January 2018

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Functional Synergy between the Transcription Factor Sp1 and the Estrogen Receptor

21 January 2018

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The cell cycle and cancer

21 January 2018

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Apoptosis in the pathogenesis and treatment of disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MC.1046

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25 November 2017

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