Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities (Q24312060)

20 October 2023

Inmaculada López-Sánchez

series ordinal

author given names

Inmaculada

author last names

López-Sánchez

1 reference

20 October 2023

Pedro A Lazo

series ordinal

author given names

Pedro A

author last names

Lazo

1 reference

Molecular & Cellular Proteomics

20 October 2023

language of work or name

English

0 references

publication date

November 2008

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published in

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volume

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issue

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page(s)

2199-214

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cites work

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c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK)

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Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK

19 March 2017

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Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo

19 March 2017

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Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells

19 March 2017

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Characterization of three paralogous members of the Mammalian vaccinia related kinase family

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MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14

19 March 2017

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Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)

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Identification of Two Novel Human Putative Serine/Threonine Kinases, VRK1 and VRK2, with Structural Similarity to Vaccinia Virus B1R Kinase

19 March 2017

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Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

19 March 2017

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Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

19 March 2017

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VRK3-mediated inactivation of ERK signaling in adult and embryonic rodent tissues

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7 April 2017

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Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient

27 September 2017

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Human VRK1 is an early response gene and its loss causes a block in cell cycle progression

27 September 2017

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Mitotic histone H3 phosphorylation by vaccinia-related kinase 1 in mammalian cells.

27 September 2017

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Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly

27 September 2017

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Negative regulation of ERK activity by VRK3-mediated activation of VHR phosphatase

27 September 2017

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27 September 2017

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VRK1 signaling pathway in the context of the proliferation phenotype in head and neck squamous cell carcinoma.

27 September 2017

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The conserved kinase NHK-1 is essential for mitotic progression and unifying acentrosomal meiotic spindles in Drosophila melanogaster

27 September 2017

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A histone code in meiosis: the histone kinase, NHK-1, is required for proper chromosomal architecture in Drosophila oocytes

27 September 2017

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Phosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformation

27 September 2017

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Importin beta: conducting a much larger cellular symphony

27 September 2017

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Importin alpha/beta and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal

27 September 2017

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The Ran GTPase regulates kinetochore function

27 September 2017

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Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

27 September 2017

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27 September 2017

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Emerging functions of p21-activated kinases in human cancer cells

27 September 2017

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Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1.

27 September 2017

1 reference

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Nucleocytoplasmic transport: Ran, beta and beyond

27 September 2017

1 reference

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Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle?

27 September 2017

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Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system

27 September 2017

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The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577208

Genetic evidence for Pak1 autoinhibition and its release by Cdc42.

27 September 2017

1 reference

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An H3 histone-specific kinase isolated from bovine thymus chromatin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577208

Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577208

Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors

30 May 2018

1 reference

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Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development.

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M700586-MCP200

Highly efficient protein expression and purification using bacterial hemoglobin fusion vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M700586-MCP200

The view from Awaji island: past, present, and future of RCC1 and the Ran GTPase system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M700586-MCP200

Phosphorylation regulates the dynamic interaction of RCC1 with chromosomes during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M700586-MCP200

Mitotic phosphorylation of histone H3 at threonine 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M700586-MCP200

The kinases MSK1 and MSK2 are required for epidermal growth factor-induced, but not tumor necrosis factor-induced, histone H3 Ser10 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M700586-MCP200

PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M700586-MCP200

Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18617507

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/18617507

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phosphorylation of histone H3 is required for proper chromosome condensation and segregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18617507

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/MCP.M700586-MCP200

1 reference

release_ysyu7a4buzbgxpxryri4vyewxe

Fatcat ID

0 references

1 reference

1 reference

1 reference