Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1 (Q24337845)

cellular response to oxidative stress

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TGF-beta activated kinase 1/MAP3K7 binding protein 1

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Mitogen-activated protein kinase kinase kinase 7

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Molecular and Cellular Biology

Sandra Blanco

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Pedro A Lazo

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Claudio Santos

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language of work or name

English

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publication date

October 2007

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published in

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volume

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issue

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page(s)

7273-83

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on focus list of Wikimedia project

ScienceSource

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cites work

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Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol

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Identification of Two Novel Human Putative Serine/Threonine Kinases, VRK1 and VRK2, with Structural Similarity to Vaccinia Virus B1R Kinase

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27 September 2017

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27 September 2017

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The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.

27 September 2017

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27 September 2017

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Sequential activation of activator protein-1-related transcription factors and JNK protein kinases may contribute to apoptotic death induced by transient hypoxia in developing brain neurons

30 May 2018

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c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia

30 May 2018

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Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.

29 November 2018

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29 November 2018

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29 November 2018

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Postconditioning attenuates cardiomyocyte apoptosis via inhibition of JNK and p38 mitogen-activated protein kinase signaling pathways

29 November 2018

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12 December 2020

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