Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair (Q24310231)

19 October 2023

Wen-Cheng Chou

Wen-Cheng

Chou

1 reference

19 October 2023

Hui-Chun Wang

Hui-Chun

Wang

1 reference

19 October 2023

Fen-Hwa Wong

Fen-Hwa

Wong

1 reference

19 October 2023

Shian-ling Ding

Shian-ling

Ding

1 reference

19 October 2023

Pei-Ei Wu

Pei-Ei

1 reference

19 October 2023

Sheau-Yann Shieh

Sheau-Yann

Shieh

1 reference

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

19 October 2023

language of work or name

English

0 references

publication date

3 December 2008

0 references

0 references

0 references

0 references

3140-50

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

DNA nucleotide excision repair-dependent signaling to checkpoint activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

N-methylpurine DNA glycosylase overexpression increases alkylation sensitivity by rapidly removing non-toxic 7-methylguanine adducts

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

The BRCT Domain Is a Phospho-Protein Binding Domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Genome maintenance mechanisms for preventing cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Cell-cycle checkpoints and cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Role of XRCC1 in the coordination and stimulation of oxidative DNA damage repair initiated by the DNA glycosylase hOGG1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Base-excision repair of oxidative DNA damage

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Chk1 and Chk2 kinases in checkpoint control and cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

The methyl methanesulfonate induced S-phase delay in XRCC1-deficient cells requires ATM and ATR.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Regulation of DNA repair throughout the cell cycle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

The DNA damage response pathways: at the crossroad of protein modifications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Radiation-induced DNA damage responses

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Mammalian single-strand break repair: mechanisms and links with chromatin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

ATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

The Fanconi Anemia/BRCA pathway: new faces in the crowd

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Breast cancer risk and the DNA double-strand break end-joining capacity of nonhomologous end-joining genes are affected by BRCA1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

The interacting pathways for prevention and repair of oxidative DNA damage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

XRCC1 and DNA strand break repair

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2599873

XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair.

27 September 2017

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2008.229

Regulation of CHK2 by DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2008.229

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2008.229

CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2008.229

Cell signaling. A touching response to damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2008.229

Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18971944

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks

1 reference

https://pubmed.ncbi.nlm.nih.gov/18971944

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genetic variation in the premature aging gene WRN: a case-control study on breast cancer susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/18971944

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2008.229

0 references

Fatcat ID

release_zrqutmg4efb6pjkyt2piusd5gu

0 references

PMC publication ID

2599873

0 references