BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP (Q34863348)

5 August 2017

title

BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP (English)

1 reference

5 August 2017

main subject

protein ubiquitination

1 reference

1 reference

Maoyi Lai

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5 August 2017

Xiaochun Yu

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5 August 2017

Shuang Fu

series ordinal

1 reference

5 August 2017

Richard Baer

series ordinal

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5 August 2017

Junjie Chen

series ordinal

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5 August 2017

publication date

1 July 2006

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5 August 2017

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

1721-1726

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Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes

5 August 2017

cites work

1 reference

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Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property

8 July 2018

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BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.

8 July 2018

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BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II.

8 July 2018

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Interactions between BRCT repeats and phosphoproteins: tangled up in two

8 July 2018

1 reference

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DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains

8 July 2018

1 reference

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BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number

8 July 2018

1 reference

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Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase

8 July 2018

1 reference

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BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

SIAH-1 interacts with CtIP and promotes its degradation by the proteasome pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

8 July 2018

1 reference

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The BRCT Domain Is a Phospho-Protein Binding Domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity

8 July 2018

1 reference

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Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Genetic analysis of BRCA1 function in a defined tumor cell line

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Characterization of a carboxy-terminal BRCA1 interacting protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1522068

26 October 2018

Identifiers

DOI

10.1101/GAD.1431006

1 reference

5 August 2017

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5 August 2017

1 reference