The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway (Q24298310)

GOA release 2020-03-11

catenin beta 1

1 reference

GOA release 2020-03-11

author name string

Giancarlo Ghiselli

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Nefeteria Coffee

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Christine E Munnery

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Revati Koratkar

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Linda D Siracusa

Journal of Biological Chemistry

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language of work or name

English

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publication date

30 May 2003

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published in

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volume

278

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issue

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page(s)

20259-67

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cites work

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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Functional interaction of beta-catenin with the transcription factor LEF-1

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Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

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Beta-catenin: a key mediator of Wnt signaling

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Id2 is a target of the beta-catenin/T cell factor pathway in colon carcinoma

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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Identification of c-MYC as a target of the APC pathway

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The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

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ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation.

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Gastrin is a target of the beta-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis

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Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

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The molecular basis of sister-chromatid cohesion

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Characterization of the components of the putative mammalian sister chromatid cohesion complex

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Chromosome cohesion, condensation, and separation

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The anaphase-promoting complex: proteolysis in mitosis and beyond

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cDNA cloning of the basement membrane chondroitin sulfate proteoglycan core protein, bamacan: a five domain structure including coiled-coil motifs

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Overexpression of bamacan/SMC3 causes transformation

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

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Complete cDNA cloning, genomic organization, chromosomal assignment, functional characterization of the promoter, and expression of the murine Bamacan gene

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Overexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators

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E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity

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Molecular architecture of SMC proteins and the yeast cohesin complex

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Destruction of the securin Pds1p occurs at the onset of anaphase during both meiotic divisions in yeast

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Mzf1 controls cell proliferation and tumorigenesis

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Homeosis and intestinal tumours in Cdx2 mutant mice

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CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling

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Signaling networks that link cell proliferation and cell fate

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Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling.

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Acetylation of beta-catenin by CREB-binding protein (CBP).

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Basement membrane and interstitial proteoglycans produced by MDCK cells correspond to those expressed in the kidney cortex

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SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

21 January 2018

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Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

21 January 2018

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Mmip1: a novel leucine zipper protein that reverses the suppressive effects of Mad family members on c-myc

21 January 2018

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The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of beta-catenin-lymphocyte enhancer-binding factor signaling

21 January 2018

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SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family

21 January 2018

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Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box

21 January 2018

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