Signaling networks that link cell proliferation and cell fate (Q34502845)

2 August 2017

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title

Signaling networks that link cell proliferation and cell fate (English)

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2 August 2017

Rosalie C Sears

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2 August 2017

Joseph R Nevins

series ordinal

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2 August 2017

language of work or name

English

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publication date

22 January 2002

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Journal of Biological Chemistry

2 August 2017

published in

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2 August 2017

volume

277

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2 August 2017

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2 August 2017

page(s)

11617-11620

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2 August 2017

cites work

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A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

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Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

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c-Myc target genes involved in cell growth, apoptosis, and metabolism

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Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

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Complex transcriptional regulatory mechanisms control expression of the E2F3 locus

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Multiple Ras functions can contribute to mammalian cell transformation

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How do small GTPase signal transduction pathways regulate cell cycle entry?

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Multiple ras effector pathways contribute to G(1) cell cycle progression

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The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

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Increasing complexity of Ras signaling.

21 January 2018

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Ras signalling and apoptosis

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

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Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

21 January 2018

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Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

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A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

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Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

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Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

21 January 2018

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Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

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Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

21 January 2018

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Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

21 January 2018

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Ras Activity Late in G1 Phase Required for p27kip1 Downregulation, Passage through the Restriction Point, and Entry into S Phase in Growth Factor-Stimulated NIH 3T3 Fibroblasts

21 January 2018

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Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation

21 January 2018

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Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

21 January 2018

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

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Reversible tumorigenesis by MYC in hematopoietic lineages

21 January 2018

1 reference

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R100063200

The Rb/E2F pathway and cancer

21 January 2018

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MYC oncogenes and human neoplastic disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R100063200

21 January 2018

Identifiers

DOI

10.1074/JBC.R100063200

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2 August 2017

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