Functional interaction of beta-catenin with the transcription factor LEF-1 (Q28286884)

Gene Ontology release 2020-05-02

J Behrens

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J P von Kries

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M Kühl

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L Bruhn

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D Wedlich

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R Grosschedl

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W Birchmeier

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

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language of work or name

English

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publication date

15 August 1996

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published in

Nature

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volume

382

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issue

6592

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page(s)

638-42

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cites work

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7 January 2021

The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules

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A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin

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A repeating amino acid motif shared by proteins with diverse cellular roles

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dishevelled and armadillo act in the wingless signalling pathway in Drosophila

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Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling

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LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

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7 January 2021

A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer

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7 January 2021

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

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7 January 2021

A novel genetic system to detect protein-protein interactions

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7 January 2021

The nuclear localization signal of lymphoid enhancer factor-1 is recognized by two differentially expressed Srp1-nuclear localization sequence receptor proteins

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Plakoglobin: a protein common to different kinds of intercellular adhering junctions

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The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

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7 January 2021

Structural basis for DNA bending by the architectural transcription factor LEF-1

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7 January 2021

Fos-Jun heterodimers and Jun homodimers bend DNA in opposite orientations: implications for transcription factor cooperativity

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Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development

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Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis.

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Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos

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7 January 2021

A new member of the frizzled family from Drosophila functions as a Wingless receptor

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7 January 2021

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

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7 January 2021

LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

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7 January 2021

The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells

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7 January 2021

Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vector

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Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

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Dominant negative expression of a cytoplasmically deleted mutant of XB/U-cadherin disturbs mesoderm migration during gastrulation in Xenopus laevis

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7 January 2021