Pages that link to "Q37388247"
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The following pages link to Laura H Heitman (Q37388247):
Displaying 50 items.
- Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions (Q27670746) (← links)
- Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength (Q27711387) (← links)
- Determination of different putative allosteric binding pockets at the lutropin receptor by using diverse drug-like low molecular weight ligands (Q34136111) (← links)
- Fragment screening of GPCRs using biophysical methods: identification of ligands of the adenosine A(2A) receptor with novel biological activity (Q34422021) (← links)
- The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity (Q36506869) (← links)
- Characterization of 12 GnRH peptide agonists - a kinetic perspective (Q36744172) (← links)
- G protein-coupled receptors of the hypothalamic-pituitary-gonadal axis: a case for Gnrh, LH, FSH, and GPR54 receptor ligands (Q37193893) (← links)
- The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor (Q37381287) (← links)
- Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists (Q37507076) (← links)
- Drug-target residence time--a case for G protein-coupled receptors (Q38189272) (← links)
- Bias in chemokine receptor signalling (Q38200224) (← links)
- Scintillation proximity assay (SPA) as a new approach to determine a ligand's kinetic profile. A case in point for the adenosine A1 receptor (Q38358474) (← links)
- Indanes--Properties, Preparation, and Presence in Ligands for G Protein Coupled Receptors (Q38505134) (← links)
- Allosteric modulation, thermodynamics and binding to wild-type and mutant (T277A) adenosine A1 receptors of LUF5831, a novel nonadenosine-like agonist (Q38756711) (← links)
- Kinetic Aspects of the Interaction between Ligand and G Protein-Coupled Receptor: The Case of the Adenosine Receptors (Q38810731) (← links)
- Equilibrium and kinetic selectivity profiling on the human adenosine receptors (Q38901485) (← links)
- When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as CCR2 antagonists (Q38911240) (← links)
- Synthesis and biological evaluation of negative allosteric modulators of the Kv11.1(hERG) channel (Q38947869) (← links)
- The Role of Target Binding Kinetics in Drug Discovery (Q38949395) (← links)
- Discovery and mapping of an intracellular antagonist binding site at the chemokine receptor CCR2. (Q38975365) (← links)
- Kinetic Profile of Neuropeptide-Receptor Interactions (Q38993975) (← links)
- Structure-kinetic relationships--an overlooked parameter in hit-to-lead optimization: a case of cyclopentylamines as chemokine receptor 2 antagonists (Q39096779) (← links)
- Kinetics for Drug Discovery: an industry-driven effort to target drug residence time (Q39244737) (← links)
- Dual-point competition association assay: a fast and high-throughput kinetic screening method for assessing ligand-receptor binding kinetics (Q39254269) (← links)
- Synthesis and biological evaluation of 2,3,5-substituted [1,2,4]thiadiazoles as allosteric modulators of adenosine receptors (Q40597031) (← links)
- Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines (Q41612048) (← links)
- Structure-Affinity Relationships and Structure-Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A3 Receptor Antagonists (Q41722014) (← links)
- A covalent antagonist for the human adenosine A2A receptor (Q41763691) (← links)
- Molecular mechanism of allosteric modulation at GPCRs: insight from a binding kinetics study at the human A1 adenosine receptor (Q42221343) (← links)
- Functional efficacy of adenosine A₂A receptor agonists is positively correlated to their receptor residence time (Q42246408) (← links)
- The Added Value of Assessing Ligand-Receptor Binding Kinetics in Drug Discovery (Q42396189) (← links)
- Sodium ion binding pocket mutations and adenosine A2A receptor function. (Q42469733) (← links)
- From receptor binding kinetics to signal transduction; a missing link in predicting in vivo drug-action (Q42620551) (← links)
- Allosteric modulators of the hERG K(+) channel: radioligand binding assays reveal allosteric characteristics of dofetilide analogs (Q42708552) (← links)
- Substituted terphenyl compounds as the first class of low molecular weight allosteric inhibitors of the luteinizing hormone receptor (Q46083680) (← links)
- A series of 2,4-disubstituted quinolines as a new class of allosteric enhancers of the adenosine A3 receptor (Q46152385) (← links)
- False positives in a reporter gene assay: identification and synthesis of substituted N-pyridin-2-ylbenzamides as competitive inhibitors of firefly luciferase (Q46469352) (← links)
- Amiloride derivatives and a nonpeptidic antagonist bind at two distinct allosteric sites in the human gonadotropin-releasing hormone receptor (Q46698860) (← links)
- Synthesis and evaluation of homodimeric GnRHR antagonists having a rigid bis-propargylated benzene core (Q46746953) (← links)
- [3H]Org 43553, the first low-molecular-weight agonistic and allosteric radioligand for the human luteinizing hormone receptor (Q46909958) (← links)
- Structure-Affinity Relationships and Structure-Kinetic Relationships of 1,2-Diarylimidazol-4-carboxamide Derivatives as Human Cannabinoid 1 Receptor Antagonists (Q47103408) (← links)
- Structural Mapping of Adenosine Receptor Mutations: Ligand Binding and Signaling Mechanisms (Q47333337) (← links)
- Allosteric Modulation of Kv11.1 (hERG) Channels Protects Against Drug-Induced Ventricular Arrhythmias (Q50520878) (← links)
- Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists (Q51019605) (← links)
- Binding kinetics of ZM241385 derivatives at the human adenosine A2A receptor (Q51750607) (← links)
- Synthesis and evaluation of homo-bivalent GnRHR ligands (Q51797304) (← links)
- Molecular Basis of Ligand Dissociation from the Adenosine A2A Receptor. (Q52884916) (← links)
- Evaluation of (4-Arylpiperidin-1-yl)cyclopentanecarboxamides As High-Affinity and Long-Residence-Time Antagonists for the CCR2 Receptor. (Q53481892) (← links)
- Label-free detection of transporter activity via GPCR signalling in living cells: A case for SLC29A1, the equilibrative nucleoside transporter 1 (Q90261793) (← links)
- Bioisosteric replacement of central 1,2,4-oxadiazole ring of high affinity CB2 ligands by regioisomeric 1,3,4-oxadiazole ring (Q90950266) (← links)