Pages that link to "Q34137893"
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The following pages link to aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation (Q34137893):
Displaying 50 items.
- The Nicastrin-like protein Nicalin regulates assembly and stability of the Nicalin-nodal modulator (NOMO) membrane protein complex (Q24294819) (← links)
- Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase (Q24298275) (← links)
- Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch (Q24307727) (← links)
- Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation (Q24314297) (← links)
- Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex (Q24318823) (← links)
- TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity (Q24321405) (← links)
- CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production (Q24523660) (← links)
- Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide production (Q24528112) (← links)
- Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components (Q24532080) (← links)
- Ubiquilin regulates presenilin endoproteolysis and modulates gamma-secretase components, Pen-2 and nicastrin (Q24537149) (← links)
- Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation (Q24541447) (← links)
- Nicalin and its binding partner Nomo are novel Nodal signaling antagonists (Q24563200) (← links)
- Pathways towards and away from Alzheimer's disease (Q24596270) (← links)
- When loss is gain: reduced presenilin proteolytic function leads to increased Abeta42/Abeta40. Talking Point on the role of presenilin mutations in Alzheimer disease (Q24676480) (← links)
- Textpresso: an ontology-based information retrieval and extraction system for biological literature (Q24793009) (← links)
- The presenilins (Q24806449) (← links)
- Stepping closer to treating Alzheimer's disease patients with BACE1 inhibitor drugs (Q26740189) (← links)
- Palmitoylation in Alzheimer's disease and other neurodegenerative diseases (Q26747019) (← links)
- Diabetes Mellitus Induces Alzheimer's Disease Pathology: Histopathological Evidence from Animal Models (Q26750648) (← links)
- Caenorhabditis elegans as a model organism to study APP function (Q26851244) (← links)
- Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease (Q26999922) (← links)
- Toward the structure of presenilin/γ-secretase and presenilin homologs (Q27002018) (← links)
- General anesthetics and β-amyloid protein (Q27010208) (← links)
- Structural biology of presenilin 1 complexes (Q27023904) (← links)
- The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity (Q27314681) (← links)
- APP processing in Alzheimer's disease (Q27694738) (← links)
- Complex regulation of γ-secretase: from obligatory to modulatory subunits (Q28080576) (← links)
- Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways (Q28081678) (← links)
- An atomic structure of human γ-secretase (Q28116260) (← links)
- A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gamma-secretase complex (Q28185671) (← links)
- GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides (Q28205921) (← links)
- The ubiquitin‐like domain of Herp is involved in Herp degradation, but not necessary for its enhancement of amyloid β‐protein generation (Q28208594) (← links)
- Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates (Q28211750) (← links)
- Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation (Q28252132) (← links)
- Proteolytic processing of Alzheimer's β-amyloid precursor protein (Q28254104) (← links)
- Presenilin 1 stabilizes the C-terminal fragment of the amyloid precursor protein independently of gamma-secretase activity (Q28256875) (← links)
- BACE1 and presenilin: two unusual aspartyl proteases involved in Alzheimer's disease (Q28257726) (← links)
- Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues (Q28262008) (← links)
- A nine-transmembrane domain topology for presenilin 1 (Q28263814) (← links)
- Trafficking and proteolytic processing of APP (Q28265871) (← links)
- The ubiquitin-proteasome system in Alzheimer's disease (Q28268311) (← links)
- Presenilin function in Caenorhabditis elegans (Q28268940) (← links)
- Assembly, trafficking and function of gamma-secretase (Q28268951) (← links)
- Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation (Q28275098) (← links)
- Pen-2 is incorporated into the gamma-secretase complex through binding to transmembrane domain 4 of presenilin 1 (Q28277779) (← links)
- Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway (Q28285387) (← links)
- Interactions of the proteins of neuronal ceroid lipofuscinosis: clues to function (Q28289653) (← links)
- Gamma-secretase complex assembly within the early secretory pathway (Q28297818) (← links)
- What is the dominant Abeta species in human brain tissue? A review (Q28301724) (← links)
- Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects (Q28478463) (← links)