Pages that link to "Q42878950"

The following pages link to NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols (Q42878950):

Displaying 50 items.

• Notch signaling: its roles and therapeutic potential in hematological malignancies (Q26765033) (← links)
• The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia (Q28075211) (← links)
• A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL). (Q31016573) (← links)
• Impact of complex NOTCH1 mutations on survival in paediatric T-cell leukaemia. (Q34120726) (← links)
• The indicative effect of Notch1 expression for the prognosis of T-cell acute lymphocytic leukemia: a systematic review (Q34152237) (← links)
• Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice (Q34186057) (← links)
• Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia (Q34213539) (← links)
• Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment. (Q34260622) (← links)
• Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia (Q34612599) (← links)
• Beyond the 2008 World Health Organization classification: the role of the hematopathology laboratory in the diagnosis and management of acute lymphoblastic leukemia (Q34755687) (← links)
• Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model (Q35085362) (← links)
• Mutational spectrum of adult T-ALL (Q35550090) (← links)
• Characterization of LEF1 High Expression and Novel Mutations in Adult Acute Lymphoblastic Leukemia (Q35571669) (← links)
• Mutations of PHF6 are associated with mutations of NOTCH1, JAK1 and rearrangement of SET-NUP214 in T-cell acute lymphoblastic leukemia (Q35596924) (← links)
• UV-Induced Wnt7a in the Human Skin Microenvironment Specifies the Fate of Neural Crest-Like Cells via Suppression of Notch (Q35602640) (← links)
• Clinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations (Q35723764) (← links)
• The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia (Q36216246) (← links)
• Impact of PTEN abnormalities on outcome in pediatric patients with T-cell acute lymphoblastic leukemia treated on the MRC UKALL2003 trial (Q36442504) (← links)
• MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies (Q36602853) (← links)
• The NOTCH signaling pathway: role in the pathogenesis of T-cell acute lymphoblastic leukemia and implication for therapy (Q36883348) (← links)
• NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia (Q36892602) (← links)
• Prognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia (Q36983745) (← links)
• The prognosis of CALM-AF10-positive adult T-cell acute lymphoblastic leukemias depends on the stage of maturation arrest (Q37273178) (← links)
• Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations (Q37662261) (← links)
• Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia (Q37802059) (← links)
• p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategies (Q37874926) (← links)
• T-cell acute lymphoblastic leukaemia: recent molecular biology findings (Q37965247) (← links)
• The molecular basis of T cell acute lymphoblastic leukemia (Q38047834) (← links)
• Lessons from next-generation sequencing analysis in hematological malignancies. (Q38123015) (← links)
• Current status and future directions of T-lymphoblastic lymphoma in children and adolescents (Q38779952) (← links)
• Interaction of Ras with p110γ is required for thymic β-selection in the mouse (Q38786279) (← links)
• Pediatric T-cell acute lymphoblastic leukemia (Q38956273) (← links)
• Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells (Q39141522) (← links)
• FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation. (Q39228542) (← links)
• Prognostic implications of mutations in NOTCH1 and FBXW7 in childhood T-ALL treated according to the NOPHO ALL-1992 and ALL-2000 protocols (Q39272383) (← links)
• AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications. (Q39463725) (← links)
• Absence of biallelic TCRγ deletion predicts induction failure and poorer outcomes in childhood T-cell acute lymphoblastic leukemia (Q39674477) (← links)
• Genetic mutational profiling analysis of T cell acute lymphoblastic leukemia reveal mutant FBXW7 as a prognostic indicator for inferior survival (Q41407670) (← links)
• The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia (Q41681563) (← links)
• MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia. (Q42330161) (← links)
• NOTCH1 mutation, TP53 alteration and myeloid antigen expression predict outcome heterogeneity in children with first relapse of T-cell acute lymphoblastic leukemia (Q42348458) (← links)
• Meta-analysis of the clinical characteristics and prognostic relevance of NOTCH1 and FBXW7 mutation in T-cell acute lymphoblastic leukemia. (Q42371637) (← links)
• The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function (Q42592644) (← links)
• MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia (Q42724150) (← links)
• B-cell receptor configuration and mutational analysis of patients with chronic lymphocytic leukaemia and trisomy 12 reveal recurrent molecular abnormalities. (Q45940002) (← links)
• T-cell Acute Lymphoblastic Leukemia Cells Display Activation of Different Survival Pathways. (Q47104126) (← links)
• NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951. (Q47259599) (← links)
• MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia (Q47402163) (← links)
• New Challenges in Targeting Signaling Pathways in Acute Lymphoblastic Leukemia by NGS Approaches: An Update. (Q52593673) (← links)
• Identification of novel NOTCH1 mutations: increasing our knowledge of the NOTCH signaling pathway. (Q53082595) (← links)