Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia (Q34213539)

31 July 2017

title

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia (English)

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31 July 2017

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lymphoblastic leukemia

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inferred from title

acute T cell leukemia

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Daniel Ribeiro

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André B Silveira

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Leonor M Sarmento

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Bruno A Cardoso

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Jörg Kobarg

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João T Barata

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Maria L Toribio

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Jules P Meijerink

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Rob Pieters

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31 July 2017

Priscila P Zenatti

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Wenqing Li

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31 July 2017

Linda Zuurbier

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31 July 2017

Milene C Silva

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31 July 2017

Maddalena Paganin

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31 July 2017

Julia Tritapoe

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Julie A Hixon

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Nádia Correia

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31 July 2017

Martin Horstmann

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Silvia R Brandalise

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31 July 2017

Adolfo A Ferrando

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Scott K Durum

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J Andrés Yunes

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31 July 2017

language of work or name

English

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publication date

4 September 2011

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

932-939

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describes a project that uses

31 July 2017

limma

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22 June 2022

https://europepmc.org/article/PMC/7424552

inferred from PubMed Central ID database lookup

cites work

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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

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NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

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Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia.

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12 December 2020

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12 December 2020

Common gamma chain-signaling cytokines promote proliferation of T-cell acute lymphoblastic leukemia

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12 December 2020

Loss of function of the homeobox gene Hoxa-9 perturbs early T-cell development and induces apoptosis in primitive thymocytes.

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12 December 2020

Negative prognostic impact of PTEN mutation in pediatric T-cell acute lymphoblastic leukemia

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12 December 2020

Interleukin-7 (IL-7) and IL-7 receptor (IL-7R) signalling complex in human solid tumours

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12 December 2020

A partial deficiency of interleukin-7R alpha is sufficient to abrogate T-cell development and cause severe combined immunodeficiency

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12 December 2020

Identifiers

DOI

10.1038/NG.924

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31 July 2017

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