Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy (Q37192616)

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scientific article published on 15 May 2010

Language	Label	Description	Also known as
English	Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy	scientific article published on 15 May 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy (English)

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Europe PubMed Central

PMC publication ID

18 August 2017

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inferred from title

7

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Marco Donia

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Europe PubMed Central

PMC publication ID

18 August 2017

5

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Jörg Bäsecke

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Europe PubMed Central

18 August 2017

PMC publication ID

Ferdinando Nicoletti

object named as

Ferdinando Nicoletti

8

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ORCID Public Data File 2021

Linda S Steelman

2

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Linda S Steelman

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Europe PubMed Central

PMC publication ID

18 August 2017

James A. McCubrey

11

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James A McCubrey

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Europe PubMed Central

PMC publication ID

18 August 2017

Alberto M Martelli

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Alberto M Martelli

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Europe PubMed Central

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18 August 2017

Stephen L Abrams

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object named as

Stephen L Abrams

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Europe PubMed Central

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18 August 2017

William H Chappell

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object named as

William Chappell

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Europe PubMed Central

PMC publication ID

18 August 2017

9

object named as

Massimo Libra

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Europe PubMed Central

PMC publication ID

18 August 2017

6

object named as

Franca Stivala

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Europe PubMed Central

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18 August 2017

author name string

John G Shelton

3

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Europe PubMed Central

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18 August 2017

publication date

15 May 2010

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Europe PubMed Central

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18 August 2017

number of pages

8

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inferred from page(s)

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Europe PubMed Central

PMC publication ID

18 August 2017

9

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Europe PubMed Central

PMC publication ID

18 August 2017

9

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1839-1846

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy

1 reference

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Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs

1 reference

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Emerging MEK inhibitors.

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Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells.

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The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior

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DNA damage-induced cell death is enhanced by progression through mitosis

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Mutant p53 rescue and modulation of p53 redox state.

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Chronic inflammation, the tumor microenvironment and carcinogenesis

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Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia

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6 September 2017

Aging: ROS or TOR.

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Ceramide promotes apoptosis in chronic myelogenous leukemia-derived K562 cells by a mechanism involving caspase-8 and JNK

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Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

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Aging, stem cells, and mammalian target of rapamycin: a prospect of pharmacologic rejuvenation of aging stem cells

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Expanding role of cyclin dependent kinases in cytokine inducible gene expression.

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Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation

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Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation

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6 September 2017

Cancer stem cells and survival pathways

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Cancer stem cells: Models, mechanisms and implications for improved treatment

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Cancer stem cell and cancer stemloids: from biology to therapy

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Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.

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Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.

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Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

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Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

1 reference

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The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

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The multiple roles of PTEN in tumor suppression

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Rapamycin decelerates cellular senescence

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrogation of factor-dependence in two IL-3-dependent cell lines can occur by two distinct mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/20436269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI-PLCbeta-1 and activated Akt levels are linked to azacitidine responsiveness in high-risk myelodysplastic syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20436269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/CC.9.9.11544

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

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