Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease (Q27671833)

From Wikidata

Jump to navigation Jump to search

The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.

scientific article

Language	Label	Description	Also known as
English	Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

based on heuristic

inferred from abstract

structural biology

1 reference

based on heuristic

inferred from abstract

3C-like proteinase [SARS-Cov]

0 references

1 reference

based on heuristic

inferred from title

Samer I Al-Gharabli

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Rolf Hilgenfeld

6

object named as

Rolf Hilgenfeld

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Lili Zhu

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Shyla George

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Marco F Schmidt

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

publication date

11 August 2011

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Antiviral Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

92

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

204-212

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21854807%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

An efficient method for the synthesis of peptide aldehyde libraries employed in the discovery of reversible SARS coronavirus main protease (SARS-CoV Mpro) inhibitors

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Mutation of Glu-166 blocks the substrate-induced dimerization of SARS coronavirus main protease.

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

The CCP4 suite: programs for protein crystallography

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

The 1.8 A structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Coot: model-building tools for molecular graphics

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Scaling and assessment of data quality

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

The substrate specificity of SARS coronavirus 3C-like proteinase

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

SARS CoV main proteinase: The monomer-dimer equilibrium dissociation constant

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Evaluating the 3C-like protease activity of SARS-Coronavirus: recommendations for standardized assays for drug discovery.

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Statistical and theoretical investigations on the directionality of nonbonded S...O interactions. Implications for molecular design and protein engineering

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide.

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Non-hydrogen bond interactions involving the methionine sulfur atom.

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

A graphical user interface to the CCP4 program suite

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Sensitized detection of inhibitory fragments and iterative development of non-peptidic protease inhibitors by dynamic ligation screening

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Recent advances in targeting viral proteases for the discovery of novel antivirals

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

pH-dependent conformational flexibility of the SARS-CoV main proteinase (M(pro)) dimer: molecular dynamics simulations and multiple X-ray structure analyses

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

A structural view of the inactivation of the SARS coronavirus main proteinase by benzotriazole esters

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Design of wide-spectrum inhibitors targeting coronavirus main proteases

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114241

13 September 2020

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27671833&oldid=1645887360"