A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase (Q27646489)

From Wikidata

Jump to navigation Jump to search

scientific article

edit

Language	Label	Description	Also known as
English	A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase	scientific article

Statements

instance of

scholarly article

0 references

title

A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase (English)

0 references

main subject

SARS-CoV-1

1 reference

based on heuristic

inferred from abstract

structural biology

of

SARS-CoV-1

1 reference

based on heuristic

inferred from abstract

3C-like proteinase [SARS-Cov]

0 references

author

Carly Huitema

object named as

Carly Huitema

series ordinal

5

0 references

Lindsay D. Eltis

object named as

Lindsay D Eltis

series ordinal

6

0 references

John Christopher Vederas

object named as

John C Vederas

series ordinal

7

0 references

author name string

Jiang Yin

series ordinal

1

0 references

Chunying Niu

series ordinal

2

0 references

Maia M Cherney

series ordinal

3

0 references

Jianmin Zhang

series ordinal

4

0 references

Michael N G James

series ordinal

8

0 references

language of work or name

English

0 references

publication date

24 August 2007

0 references

published in

Journal of Molecular Biology

0 references

volume

371

0 references

issue

4

0 references

page(s)

1060-74

0 references

cites work

Aetiology: Koch's postulates fulfilled for SARS virus

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Identification of polypeptides encoded in open reading frame 1b of the putative polymerase gene of the murine coronavirus mouse hepatitis virus A59

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Details of the acyl-enzyme intermediate and the oxyanion hole in serine protease catalysis

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Design of wide-spectrum inhibitors targeting coronavirus main proteases

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Mechanism of the maturation process of SARS-CoV 3CL protease

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease.

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide.

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Synthesis and evaluation of keto-glutamine analogues as inhibitors of hepatitis A virus 3C proteinase

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

A norovirus protease structure provides insights into active and substrate binding site integrity

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Subangstrom crystallography reveals that short ionic hydrogen bonds, and not a His-Asp low-barrier hydrogen bond, stabilize the transition state in serine protease catalysis.

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Interaction of the peptide CF3-Leu-Ala-NH-C6H4-CF3 (TFLA) with porcine pancreatic elastase. X-ray studies at 1.8 A

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Chloroketone hydrolysis by chymotrypsin and N-methylhistidyl-57-chymotrypsin: implications for the mechanism of chymotrypsin inactivation by chloroketones

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Theoretical studies on the deacylation step of serine protease catalysis in the gas phase, in solution, and in elastase

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Locating the catalytic water molecule in serine proteases

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

The CCP4 suite: programs for protein crystallography

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Use of a fluorescence plate reader for measuring kinetic parameters with inner filter effect correction

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

On the size of the active site in proteases. I. Papain

1 reference

stated in

PubMed Central

reference URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094781

retrieved

13 September 2020

Identifiers

DOI

10.1016/J.JMB.2007.06.001

0 references

PMC publication ID

7094781

0 references

PubMed publication ID

17599357

0 references

 

Sitelinks

Wikipedia(0 entries)

edit

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27646489&oldid=1645887009"