[go: up one dir, main page]
KEGG   Homo sapiens (human): 59345
Entry
59345             CDS       T01001                                 
Symbol
GNB4, CMTD1F, HG2B
Name
(RefSeq) G protein subunit beta 4
  KO
K04538  guanine nucleotide-binding protein subunit beta-4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06161  Human immunodeficiency virus 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167  Human cytomegalovirus (HCMV)
nt06224  CXCR signaling (cancer)
nt06530  PI3K signaling
nt06533  Chemokine signaling
  Element
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00399  CCR2-GNB/G-PI3K-NFKB signaling pathway
N00400  HCMV US28 to GNB/G-PI3K-NFKB signaling pathway
N00408  LPAR-GNB/G-Rho signaling pathway
N00409  HCMV UL33 to GNB/G-Rho signaling pathway
N00413  CXCR4-GNB/G-PLCB-PKC signaling pathway
N00428  CCR5-GNB/G-PLCB/G-PKC signaling pathway
N00433  CXCR4-GNB/G-RAC signaling pathway
N00434  HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
N01657  GPCR-PI3K signaling pathway
N01746  CCR/CXCR-GNB/G-PI3K signaling pathway
N01769  CCR5-GNB/G-PLCB/G signaling pathway
N01770  CCR2-GNB/G-PI3K signaling pathway
N01771  CXCR4-GNB/G signaling pathway
Disease
H00264  Charcot-Marie-Tooth disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    59345 (GNB4)
   04151 PI3K-Akt signaling pathway
    59345 (GNB4)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    59345 (GNB4)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    59345 (GNB4)
  09156 Nervous system
   04724 Glutamatergic synapse
    59345 (GNB4)
   04727 GABAergic synapse
    59345 (GNB4)
   04725 Cholinergic synapse
    59345 (GNB4)
   04728 Dopaminergic synapse
    59345 (GNB4)
   04726 Serotonergic synapse
    59345 (GNB4)
   04723 Retrograde endocannabinoid signaling
    59345 (GNB4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    59345 (GNB4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    59345 (GNB4)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    59345 (GNB4)
   05163 Human cytomegalovirus infection
    59345 (GNB4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    59345 (GNB4)
  09165 Substance dependence
   05032 Morphine addiction
    59345 (GNB4)
   05034 Alcoholism
    59345 (GNB4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    59345 (GNB4)
   04031 GTP-binding proteins [BR:hsa04031]
    59345 (GNB4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   59345 (GNB4)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Beta Subunits
   Beta [OT]
    59345 (GNB4)
SSDB
Motif
Pfam: WD40 WD40_Prp19 WD40_CDC20-Fz Beta-prop_CAF1B_HIR1 WD40_WDHD1_1st EIF3I Beta-prop_EML_2 WDR55 Beta-prop_WD40_POC16_2nd Beta-prop_EML ANAPC4_WD40 WD40_MABP1-WDR62_2nd Beta-prop_IFT122_1st NBCH_WD40 Beta-prop_SPT8 Beta-prop_SCAP WD40_MABP1-WDR62_1st Beta-prop_RIG_2nd Beta-prop_DCAF12 Beta-prop_WDR19_1st Beta-prop_Vps41 WDR90_beta-prop_4th Beta-prop_WDR75_1st Beta-prop_DCAF4 Beta-prop_IFT140_1st Beta-prop_EIPR1 Beta-prop_WDR35_TULP_N WD40_like eIF2A YNCE Beta-prop_HPS5
Other DBs
NCBI-GeneID: 59345
NCBI-ProteinID: NP_067642
OMIM: 610863
HGNC: 20731
Ensembl: ENSG00000114450
UniProt: Q9HAV0
LinkDB
Position
3:complement(179396088..179527798)
AA seq 340 aa
MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYA
MHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTF
TGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYA
FATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL
KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN
NT seq 1023 nt   +upstreamnt  +downstreamnt
atgagcgaactggaacagttgaggcaagaagcagaacaactgcggaatcagattcaggat
gctcggaaagcatgtaatgatgcaacgcttgttcagattacatcaaatatggactctgtg
ggtcgaatacaaatgcgaacaagacgtacactgaggggccacctagctaaaatctatgct
atgcattggggatacgattccaggctgctagtcagtgcttctcaagatggaaaattaatt
atttgggatagctatacaacaaataagatgcatgctattcctttgaggtcctcctgggtg
atgacctgtgcttatgctccctctggtaattatgttgcctgtggaggcttggacaacatc
tgctctatatataacttaaagaccagagagggaaatgtgagagtaagccgagagttgcca
ggtcacacagggtacttgtcctgctgtcgttttttagatgacagccaaattgttacaagt
tcaggagatacaacttgtgctttatgggacatcgaaactgcccagcagaccaccacattc
actgggcattctggagatgtgatgagtctttctttgagtcctgacatgaggacttttgtt
tctggtgcttgtgatgcctcttccaaattatgggatattcgagatggaatgtgtagacag
tctttcacgggacatgtctcagatatcaatgctgtcagttttttcccaaatggatatgcc
ttcgccactggctctgatgatgccacttgccggctctttgaccttcgtgcagatcaagag
ttattattgtattctcatgacaatatcatctgtggaatcacttctgtagccttctcaaaa
agtgggcgtctcttgttggctggttacgatgactttaattgtaatgtatgggacacgcta
aaaggagatcgtgcaggtgtccttgctggtcatgacaaccgtgtgagctgcttaggtgta
actgatgatggcatggctgtggcaacaggctcttgggacagttttcttagaatctggaat
taa

DBGET integrated database retrieval system