Entry Name KSHV vGPCR to GNB/G-ERK signaling pathway
Definition vGPCR -> GNB/G
Expanded K21667 -> (2782,2783,2784,59345,10681,54331,2785,2786,2787,2788,94235,2790,2791,55970,51764,2792,2793)
Class nt06533 Chemokine signaling
nt06224 CXCR signaling (cancer)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
Type Pathogen
Pathway hsa05167 Kaposi sarcoma-associated herpesvirus infection
Disease Gene 2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
Perturbant K21667 (vGPCR) vGPCR; KSHV G-protein coupled receptor
Reference Authors Mesri EA, Cesarman E, Boshoff C
Title Kaposi's sarcoma and its associated herpesvirus.
Journal Reference Authors Sodhi A, Montaner S, Patel V, Zohar M, Bais C, Mesri EA, Gutkind JS
Title The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha.
Journal Cancer Res 60:4873-80 (2000)
Reference Authors Abere B, Schulz TF
Title KSHV non-structural membrane proteins involved in the activation of intracellular signaling pathways and the pathogenesis of Kaposi's sarcoma.
Journal Reference Authors Sodhi A, Montaner S, Gutkind JS
Title Viral hijacking of G-protein-coupled-receptor signalling networks.
Journal LinkDB All DBs