Entry |
|
Symbol |
F2
|
Name |
coagulation factor II (thrombin) [EC: 3.4.21.5]
|
Pathway |
map04072 | Phospholipase D signaling pathway |
map04080 | Neuroactive ligand-receptor interaction |
map04610 | Complement and coagulation cascades |
map04810 | Regulation of actin cytoskeleton |
map05130 | Pathogenic Escherichia coli infection |
|
Disease |
H00223 | Inherited thrombophilia |
H01254 | Congenital prothrombin deficiency |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
K01313 F2; coagulation factor II (thrombin)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
K01313 F2; coagulation factor II (thrombin)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
K01313 F2; coagulation factor II (thrombin)
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
K01313 F2; coagulation factor II (thrombin)
04611 Platelet activation
K01313 F2; coagulation factor II (thrombin)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
K01313 F2; coagulation factor II (thrombin)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
K01313 F2; coagulation factor II (thrombin)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
K01313 F2; coagulation factor II (thrombin)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors
K01313 F2; coagulation factor II (thrombin)
09183 Protein families: signaling and cellular processes
04147 Exosome
K01313 F2; coagulation factor II (thrombin)
00536 Glycosaminoglycan binding proteins
K01313 F2; coagulation factor II (thrombin)
Enzymes [BR:ko01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.5 thrombin
K01313 F2; coagulation factor II (thrombin)
Peptidases and inhibitors [BR:ko01002]
Serine peptidases
Family S1: chymotrypsin family
K01313 F2; coagulation factor II (thrombin)
Exosome [BR:ko04147]
Exosomal proteins
Exosomal proteins of hepatic cells
K01313 F2; coagulation factor II (thrombin)
Glycosaminoglycan binding proteins [BR:ko00536]
Heparan sulfate / Heparin
Coagulation and fibrinolysis
K01313 F2; coagulation factor II (thrombin)
|
Genes |
» show all
|
Reference |
|
Authors |
MacGillivray RT, Davie EW |
Title |
Characterization of bovine prothrombin mRNA and its translation product. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Glenn KC, Frost GH, Bergmann JS, Carney DH |
Title |
Synthetic peptides bind to high-affinity thrombin receptors and modulate thrombin mitogenesis. |
Journal |
Pept Res 1:65-73 (1988) |
LinkDB |
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