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KEGG   Pongo abelii (Sumatran orangutan): 100173859
Entry
100173859         CDS       T01416                                 
Symbol
F2
Name
(RefSeq) prothrombin precursor
  KO
K01313  coagulation factor II (thrombin) [EC:3.4.21.5]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04072  Phospholipase D signaling pathway
pon04080  Neuroactive ligand-receptor interaction
pon04610  Complement and coagulation cascades
pon04611  Platelet activation
pon04810  Regulation of actin cytoskeleton
pon05171  Coronavirus disease - COVID-19
pon05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    100173859 (F2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    100173859 (F2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    100173859 (F2)
   04611 Platelet activation
    100173859 (F2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100173859 (F2)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100173859 (F2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pon01002]
    100173859 (F2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pon04147]
    100173859 (F2)
   00536 Glycosaminoglycan binding proteins [BR:pon00536]
    100173859 (F2)
Enzymes [BR:pon01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.5  thrombin
     100173859 (F2)
Peptidases and inhibitors [BR:pon01002]
 Serine peptidases
  Family S1: chymotrypsin family
   100173859 (F2)
Exosome [BR:pon04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   100173859 (F2)
Glycosaminoglycan binding proteins [BR:pon00536]
 Heparan sulfate / Heparin
  Coagulation and fibrinolysis
   100173859 (F2)
SSDB
Motif
Pfam: Trypsin Kringle Thrombin_light Gla DUF1986 Trypsin_2
Other DBs
NCBI-GeneID: 100173859
NCBI-ProteinID: NP_001126851
Ensembl: ENSPPYG00000003317
UniProt: Q5R537 Q5NVS1
LinkDB
Position
9:complement(20398724..20419123)
AA seq 623 aa
MAHVRGLQLPGCLALAALCTLVHSQHVFLAPQQALSLLQRVRRANSVFLEEVRKGNLERE
CVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGH
LNITQSGIQCQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQ
ECSIPVCGQDQVTVAMTPRSEGSGVNLSPPSEQCVPDRGQQYQGRLAVTTHGLPCLAWAS
AQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAMEEET
GGGLDEDPDRAIEGRTATSEYQTFFDPRTFGSGEADCGLRPLFEKKSLEDKTERELLESY
IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGATLISDRWVLTAAHCLLYPPWDKNFTE
NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH
PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKVQPSVLQVVNLPIVERPVCKDS
TRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNCWYQMGIVSWGEGCDRDGK
YGFYTHVFRLKKWIQKVIDQFGE
NT seq 1872 nt   +upstreamnt  +downstreamnt
atggcgcacgtccgaggcctgcagctgcctggctgcctggccctagctgccctgtgtacc
cttgtgcacagccagcatgtgttcctggctcctcagcaagcgctgtcgctgctccagcgg
gtccggcgagccaacagcgtctttctggaggaggtgcgcaagggcaacctggagcgagag
tgcgtggaggagacctgcagctacgaggaggccttcgaggctctggagtcctccacggct
acggatgtgttctgggccaagtacacagcttgtgagacagctaggacgcctcgagataag
cttgcggcatgtctggaaggtaactgtgctgagggtctgggtacgaactaccgagggcat
ctaaacatcacccagtcaggcattcagtgccagctatggaggagtcgctacccacataag
cctgaaatcaactccaccacccatcccggggccgacctgcaggagaatttctgccgcaac
cctgacagcagcaccacgggaccctggtgctacactacagaccccaccgtgaggaggcag
gaatgcagcatccctgtctgtggccaggatcaagtcactgtagcgatgactccacgctcc
gaaggctccggtgtgaatctgtcacctccatcagagcagtgtgtccctgatcgggggcag
cagtaccaggggcgcctggcggtgaccacacatgggctcccctgcctggcctgggccagc
gcacaggccaaggccctgagcaagcaccaggacttcaactcggccgtgcagctggtggag
aacttctgccgcaacccagatggggatgaggagggcgtgtggtgctatgtggccgggaag
cctggcgactttgggtactgcgacctcaactattgcgaggaggccatggaggaggagaca
ggaggtgggctggacgaggacccagacagggccatcgaagggcgtaccgccaccagtgag
taccagactttcttcgatccgaggacctttggctcgggagaggcagactgtgggctgcga
cctctgtttgagaagaagtcgctggaggacaaaaccgaaagagagctcctggaatcctac
atcgacgggcgcattgtggagggctcggatgcagagatcggcatgtcaccttggcaggtg
atgcttttccggaagagtccccaggagctgctgtgtggggccaccctcatcagtgaccgc
tgggtcctcaccgccgcccactgcctcctgtacccaccctgggacaagaacttcaccgag
aatgaccttctggtgcgcattggcaagcactcccgcaccaggtacgagcgaaacattgaa
aagatatccatgttggaaaagatctacatccaccccaggtacaactggcgggagaacctg
gaccgggacattgccctgatgaagctgaagaagcccgttgccttcagcgactacattcac
cctgtgtgtctgcccgacagggagacggcagccagcttgctccaggctggatacaagggg
cgggtgacaggctggggcaacctgaaggagacgtggacagccaacgttggtaaggtgcag
cccagtgtcctgcaggtggtgaacctgcccatcgtggagcggccggtctgcaaggactcc
acccggatccgcatcactgacaacatgttctgtgctggttacaagcctgatgaagggaaa
cgaggggatgcctgtgaaggtgacagcgggggaccctttgtcatgaagagcccctttaac
aactgctggtatcaaatgggcatcgtctcatggggtgaaggctgtgaccgggatgggaaa
tatggcttctacacacacgtgttccgcctgaagaagtggatacagaaggtcattgatcag
tttggagagtag

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