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KEGG   Hyaena hyaena (striped hyena): 120228398
Entry
120228398         CDS       T07257                                 
Symbol
F2
Name
(RefSeq) prothrombin
  KO
K01313  coagulation factor II (thrombin) [EC:3.4.21.5]
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv04072  Phospholipase D signaling pathway
hhv04080  Neuroactive ligand-receptor interaction
hhv04610  Complement and coagulation cascades
hhv04611  Platelet activation
hhv04810  Regulation of actin cytoskeleton
hhv05171  Coronavirus disease - COVID-19
hhv05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    120228398 (F2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    120228398 (F2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    120228398 (F2)
   04611 Platelet activation
    120228398 (F2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    120228398 (F2)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    120228398 (F2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hhv01002]
    120228398 (F2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hhv04147]
    120228398 (F2)
   00536 Glycosaminoglycan binding proteins [BR:hhv00536]
    120228398 (F2)
Enzymes [BR:hhv01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.5  thrombin
     120228398 (F2)
Peptidases and inhibitors [BR:hhv01002]
 Serine peptidases
  Family S1: chymotrypsin family
   120228398 (F2)
Exosome [BR:hhv04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   120228398 (F2)
Glycosaminoglycan binding proteins [BR:hhv00536]
 Heparan sulfate / Heparin
  Coagulation and fibrinolysis
   120228398 (F2)
SSDB
Motif
Pfam: Trypsin Kringle Thrombin_light Gla DUF1986 Trypsin_2
Other DBs
NCBI-GeneID: 120228398
NCBI-ProteinID: XP_039082640
LinkDB
Position
Unknown
AA seq 599 aa
MGQVFLAPQQALSLLQRVRRANSGFLEEVRKGNLERECVEEVCSYEEAFEALESSSDTDI
FWAKYVACESVRKPREKLVECLEGSCAEGLGMNYRGNVNFTRSGIECQLWRSRYPHKPEI
NSTTHPGADLQENFCRNPDGSTTGPWCYTTDPTVRREECSIPVCGQGGVTVQQTPRSRNS
TRNLPAASDSCIPDRGRYYRGRLAVTTYGSPCLAWDSSQAKALSKNQDFNPLVPLEGNFC
RNPDGDEEGAWCYVAGEAGVFEYCNLDYCEERVEDVGYEQAQDPDAPIEGRTTTQEFQTV
FNEKTFGAGEADCGLRPLFEKKSVKDKTEKELLDSYITGRIVEGWDAEIGIAPWQVMLFR
KSPQELLCGASLISDRWVLTAAHCLLYPPWDKNYTENDLLVRIGKHSRTRYERGIEKISM
LEKIYIHPRYNWRENLDRDIALLKLKKPITFSNYIHPVCLPDKDTVTRLIQSGYKGRVTG
WGNLKETWKASVGEVQPSVLQVVNLPLVEQPICRASTRIRITDNMFCAGFKPSEGKQGDA
CEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRNGKYGFYTHVFRLKRWIRKVIDQSGS
NT seq 1800 nt   +upstreamnt  +downstreamnt
atgggccaggtgttcctggcccctcagcaagcactatcgctgctccagcgggtccgacgt
gccaatagtggcttcctggaggaagtacgcaagggcaacctggagcgagagtgtgtggag
gaggtgtgcagctacgaggaggcctttgaggccctggagtcttcctctgacacggatata
ttctgggccaagtacgtagcttgtgagtcggtgaggaaacctcgagaaaagctcgtggaa
tgtctggaaggtagctgtgctgaaggtctgggtatgaattaccgagggaacgtgaacttc
acccggtcaggcatcgagtgccagctatggaggagtcgctacccacataagcctgaaatc
aactctactacccaccccggggccgacctgcaggagaatttctgccgcaacccagatggc
agcaccactgggccctggtgttatactacagaccccactgtgcggagggaagagtgcagc
atccccgtctgtggccaggggggcgtgactgtacagcagaccccacgctccagaaactcc
acgaggaatctgccagctgcatcggactcctgcatccctgaccgtggccggtactaccgc
ggtcgcctagcagtgaccacatatgggtccccctgcctggcctgggacagcagtcaggcc
aaggccctgagcaagaaccaggacttcaaccctttggtgccgctggaggggaacttctgc
cgcaacccggacggcgacgaggagggcgcgtggtgttacgtggccggagaggctggtgtc
ttcgagtactgcaacctggactactgcgaggagcgggtagaggacgtgggctacgagcag
gcccaggacccggacgcgcccatcgagggacgcaccacgactcaggagttccagaccgtc
tttaatgagaagaccttcggcgccggggaggcagactgtgggctgaggcctctgttcgag
aagaagtcggtgaaggacaaaacagaaaaggagcttctggattcctacatcaccgggcgc
atcgtggagggttgggacgcggagattggcatcgcaccctggcaggtgatgcttttccgg
aagagtcctcaggaactgctgtgtggggccagcctcattagtgaccgctgggtcctcacc
gctgcccactgtctcctgtacccgccgtgggacaagaactacactgagaatgaccttctg
gtgcgcattggcaagcactcccgcaccaggtacgagcgaggcatcgaaaagatctccatg
ctggaaaagatctacatccacccgaggtacaactggagggaaaacttggaccgtgacatt
gccctgctgaagctcaagaagcccatcaccttcagcaactacatccaccccgtgtgcctg
cctgacaaggacacagtgaccagactgatccagagtggatacaaagggcgggtaacgggc
tggggcaacctgaaggagacgtggaaggccagcgttggtgaggtgcagcccagtgtcctg
caggtggtgaacttgccgcttgtggagcagccaatctgcagggcgtccacccggatccgc
atcaccgacaacatgttctgcgctggtttcaagcccagtgaagggaagcaaggggatgct
tgtgaaggcgacagtgggggaccctttgtcatgaagagccccttcaacaaccgctggtat
caaatgggcatcgtctcatggggtgaaggctgtgacaggaatggaaaatatggcttctat
acacacgtgttccgcctgaagaggtggatacggaaggtcattgatcagtctggaagttag

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