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KEGG   Loxodonta africana (African savanna elephant): 100666651
Entry
100666651         CDS       T04351                                 
Symbol
F2
Name
(RefSeq) prothrombin
  KO
K01313  coagulation factor II (thrombin) [EC:3.4.21.5]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04072  Phospholipase D signaling pathway
lav04080  Neuroactive ligand-receptor interaction
lav04610  Complement and coagulation cascades
lav04611  Platelet activation
lav04810  Regulation of actin cytoskeleton
lav05171  Coronavirus disease - COVID-19
lav05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    100666651 (F2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    100666651 (F2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    100666651 (F2)
   04611 Platelet activation
    100666651 (F2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100666651 (F2)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100666651 (F2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:lav01002]
    100666651 (F2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lav04147]
    100666651 (F2)
   00536 Glycosaminoglycan binding proteins [BR:lav00536]
    100666651 (F2)
Enzymes [BR:lav01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.5  thrombin
     100666651 (F2)
Peptidases and inhibitors [BR:lav01002]
 Serine peptidases
  Family S1: chymotrypsin family
   100666651 (F2)
Exosome [BR:lav04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   100666651 (F2)
Glycosaminoglycan binding proteins [BR:lav00536]
 Heparan sulfate / Heparin
  Coagulation and fibrinolysis
   100666651 (F2)
SSDB
Motif
Pfam: Trypsin Kringle Thrombin_light Gla DUF1986 Trypsin_2
Other DBs
NCBI-GeneID: 100666651
NCBI-ProteinID: XP_003412151
LinkDB
Position
Unknown
AA seq 616 aa
MAHVRGPRLPGCLALAALFSLVHSQHVFLAPQQALSMLQRVRRANSGFLEEMRKGNLERE
CVEEQCSYEEAFEALESPSDTEAFWVKYTACEPVRTPRENLVECLEGNCAVGLGTNYHGN
VSFTRSGIECQLWRSRYPHKPEINFTAYHEAYLKENFCRNPDSSTTGPWCYTTDPTVRRE
ECSIPVCGGEGVTVALTPRSRVKPSPPSELCVLDRGQQYQGSLAVTTQGSPCLAWASSEA
KALSKDLDFSKSVPLVENYCRNPDGDAEGAWCYVAGKPGDFEYCDLNYCEEPLEEEAGDG
LDEDPDASIQGRTTAEEFQSFFNPRTFGAGEADCGLRPLFEKKSLEDKREKELLDSYIAG
RIVEGWDAEQGIAPWQVMLFRKSPQELLCGASLISDRWILTAAHCLLYPPWDKNFTENDL
LVRLGKHSRTRYERNFEKISMLEKIYIHPRYNWRDNLDRDIALLKLKKPIAFSNYIHPVC
LPDKETAARLLQAGYKGRVTGWGNLKETWTASTSEVQPSVLQVVHLPIVERPVCKASTRI
RITDNMFCAGFKPNEGQRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGF
YTHVFRLKRWILKVVG
NT seq 1851 nt   +upstreamnt  +downstreamnt
atggcgcacgtccgaggcccgcgcctgcctggctgcctggccctagctgccctgttcagc
cttgtgcacagccagcatgtgttcctggcccctcagcaagcactgtcgatgctccagcgg
gtccgccgtgccaacagcggcttcctggaggagatgcgcaaaggtaacctggagcgagag
tgcgtggaggagcagtgcagctatgaggaggctttcgaggccctggagtctcccagtgac
acggaagcattctgggtcaagtacacagcttgtgagccagtgaggacacctcgagaaaac
ctcgtggaatgtctggaagggaactgcgctgtgggtctgggcacaaactaccatgggaac
gtgagcttcacccggtcaggcatcgagtgccagctctggaggagtcgctatccacataaa
cctgaaatcaacttcaccgcctaccacgaggcctacctgaaggagaatttctgccgcaac
ccagatagcagcactacggggccctggtgctacactacagaccccaccgtgcggagggaa
gagtgcagcatccctgtgtgtggcggggagggtgtcactgtggcactgaccccacgctcc
agggtgaagccctcacccccatctgagctgtgtgtcctggatcgtggccagcagtaccag
ggtagcctggcggtgaccacacaaggctccccctgcctggcctgggccagcagtgaggcc
aaggccctgagcaaggacctggatttcagcaagtcagtgcctctggtggagaactactgc
cggaatccagacggggacgctgagggcgcgtggtgctatgtggccgggaagcctggtgac
tttgagtactgcgacctcaactactgcgaggaacccctggaggaggaggctggagacggg
ttggacgaggaccccgacgcgtccatccaagggcgcaccaccgctgaggagttccagagc
tttttcaacccacggaccttcggcgccggggaggcagactgtgggctgcggcctctgttt
gagaagaagtcgctagaggacaagagggaaaaggagctgctggattcctacatcgccggg
cgcatcgtggagggttgggatgcggagcaaggcatcgcgccctggcaggtgatgcttttc
cggaagagtccccaggagctgctgtgtggggccagccttatcagtgaccgctggatcctc
accgcagcccactgcctgctgtacccaccgtgggacaagaatttcaccgagaacgacctt
ttggtgcgccttggcaagcactcccgtaccaggtatgagcggaactttgagaagatctcc
atgctggagaagatctatatccatcccaggtacaactggagggacaacctggaccgggac
atcgccctgctgaagctcaagaagcccatcgccttcagtaactacattcaccctgtgtgc
ctgcctgacaaggagactgcagcgagattgctccaggctggatacaaagggcgggtgacc
ggctggggcaacctgaaggagacgtggacggccagcactagcgaggtgcagcccagtgtc
ctgcaggtggtgcacctgcccatcgtggagaggccagtctgcaaggcgtccacccgcatc
cgcatcacagacaacatgttctgtgctggtttcaagcccaatgaagggcaacgaggggat
gcttgtgaaggtgacagtgggggaccctttgtcatgaagagtccctttaacaaccgctgg
tatcaaatgggcatcgtttcgtggggtgaaggctgtgaccgggatgggaaatatggcttc
tacacacatgtgttccgcctgaagaggtggatactgaaggttgttggttga

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