(Q36423933)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16543937%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

review article

1 reference

title

Dissecting p53-dependent apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16543937%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16543937%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16543937%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

J E Chipuk

1 reference

14 August 2017

D R Green

series ordinal

1 reference

14 August 2017

publication date

1 June 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16543937%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

18 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16543937%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16543937%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16543937%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

994-1002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16543937%20AND%20SRC:MED&resulttype=core&format=json

The p53 story: layers of complexity

18 January 2020

cites work

1 reference

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21 January 2018

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Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis

21 January 2018

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Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction

21 January 2018

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21 January 2018

Surfing the p53 network

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Regulation of p53 responses by post-translational modifications

21 January 2018

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

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PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

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BID regulation by p53 contributes to chemosensitivity

21 January 2018

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p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

21 January 2018

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Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

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p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

21 January 2018

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KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

21 January 2018

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Transcription, apoptosis and p53: catch-22.

21 January 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

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Tumor spectrum analysis in p53-mutant mice

21 January 2018

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Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

21 January 2018

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Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

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Dissecting p53 tumor suppressor functions in vivo

21 January 2018

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p53QS: an old mutant teaches us new tricks

21 January 2018

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The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality

21 January 2018

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Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

21 January 2018

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Drosophila p53 binds a damage response element at the reaper locus

21 January 2018

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Identification and characterization of a p53 homologue in Drosophila melanogaster

21 January 2018

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Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.

21 January 2018

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BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

21 January 2018

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PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

21 January 2018

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Integral role of Noxa in p53-mediated apoptotic response

21 January 2018

1 reference

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

21 January 2018

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

21 January 2018

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

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p53 has a direct apoptogenic role at the mitochondria

21 January 2018

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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

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The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

21 January 2018

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Mitochondrial localization of p53 during adenovirus infection and regulation of its activity by E1B-19K.

21 January 2018

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Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells

21 January 2018

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Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

21 January 2018

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Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

21 January 2018

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In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

21 January 2018

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Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.

21 January 2018

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Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells

21 January 2018

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Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

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Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

21 January 2018

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Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

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The role of p53 in hypoxia-induced apoptosis

21 January 2018

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Y-box factor YB1 controls p53 apoptotic function

21 January 2018

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Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.

21 January 2018

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Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis

21 January 2018

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The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

21 January 2018

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The ASPP family: deciding between life and death after DNA damage

21 January 2018

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ASPP proteins specifically stimulate the apoptotic function of p53

21 January 2018

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iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

21 January 2018

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The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M

21 January 2018

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Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain.

21 January 2018

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Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

21 January 2018

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Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.

21 January 2018

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

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p53 Activation by small molecules: application in oncology

21 January 2018

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

21 January 2018

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

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Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

21 January 2018

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7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

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7 January 2021

p53 is associated with cellular microtubules and is transported to the nucleus by dynein

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7 January 2021

Apoptosis in thyroid neoplasms: relationship with p53 and bcl-2 expression

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7 January 2021

Pharmacological rescue of mutant p53 conformation and function

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7 January 2021