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English
Apaf-1 is a transcriptional target for E2F and p53
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title
Apaf-1 is a transcriptional target for E2F and p53
(English)
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author
Francesco Cecconi
object named as
Francesco Cecconi
series ordinal
6
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Kristian Helin
object named as
Kristian Helin
series ordinal
8
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author name string
M. Cristina Moroni
series ordinal
1
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Emma S. Hickman
series ordinal
2
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Eros Lazzerini Denchi
series ordinal
3
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Greta Caprara
series ordinal
4
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Elena Colli
series ordinal
5
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Heiko Müller
series ordinal
7
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publication date
June 2001
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published in
Nature Cell Biology
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volume
3
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issue
6
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page(s)
552-558
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cites work
Cancer cell cycles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
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inferred from DOI database lookup
The Hallmarks of Cancer
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma gene family in differentiation and development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation of E2F by pRB-family proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 and E2F-1 cooperate to mediate apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of DNA synthesis and apoptosis are separable functions of E2F-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1-induced p53-independent apoptosis in transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for the p53 homologue p73 in E2F-1-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p14ARF links the tumour suppressors RB and p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor surveillance via the ARF-p53 pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p73 is a simian [correction of human] p53-related protein that can induce apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The biochemistry of apoptosis
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-9 and APAF-1 form an active holoenzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A matter of life and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the cyclin E gene by transcription factor E2F1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogene-dependent apoptosis is mediated by caspase-9.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35078527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/35078527
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PubMed publication ID
11389439
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