(Q34571596)

3 August 2017

title

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging (English)

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3 August 2017

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3 August 2017

Elizabeth H Blackburn

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3 August 2017

Jack W Szostak

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3 August 2017

language of work or name

English

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publication date

1 October 2006

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3 August 2017

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

1133-1138

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Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Origin of Concatemeric T7DNA

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

The molecular structure of centromeres and telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Nucleotide sequence analysis of DNA. II. Complete nucleotide sequence of the cohesive ends of bacteriophage lambda DNA.

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Amplification of the rRNA Genes in Tetrahymena

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Tandemly repeated C-C-C-C-A-A hexanucleotide of Tetrahymena rDNA is present elsewhere in the genome and may be related to the alteration of the somatic genome

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

A family of inverted repeat sequences and specific single-strand gaps at the termini of the Physarum rDNA palindrome

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

An irregular satellite sequence is found at the termini of the linear extrachromosomal rDNA in Dictyostelium discoideum

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

DNA termini in ciliate macronuclei

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Single extrachromosomal ribosomal RNA gene copies are synthesized during amplification of the rDNA in Tetrahymena

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Sequence-specific fragmentation of macronuclear DNA in a holotrichous ciliate

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3' terminus

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Inverted terminal repeats are added to genes during macronuclear development in Oxytricha nova

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Yeast transformation: a model system for the study of recombination

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Cloning yeast telomeres on linear plasmid vectors

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

DNA sequences of telomeres maintained in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Construction of artificial chromosomes in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Chromosome length controls mitotic chromosome segregation in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

An alternative pathway for meiotic chromosome segregation in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Growth of chromosome ends in multiplying trypanosomes

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Unusual DNA sequences associated with the ends of yeast chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

A mutant with a defect in telomere elongation leads to senescence in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

https://api.crossref.org/works/10.1038%2FNM1006-1133

1 reference

7 January 2021

Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

The telomerase reverse transcriptase: components and regulation

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Reverse transcriptase motifs in the catalytic subunit of telomerase

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Hypervariable telomeric sequences from the human sex chromosomes are pseudoautosomal

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Telomeric repeat from T. thermophila cross hybridizes with human telomeres

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Telomeres shorten during ageing of human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

For better or worse? Telomerase inhibition and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Secondary structure of vertebrate telomerase RNA

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' end

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

A telomerase component is defective in the human disease dyskeratosis congenita

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Telomerase RNA structure and function: implications for dyskeratosis congenita.

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

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https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC.

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Short telomeres, even in the presence of telomerase, limit tissue renewal capacity

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1133

7 January 2021

Identifiers

DOI

10.1038/NM1006-1133

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Dimensions Publication ID

3 August 2017

1034665185

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1 reference