(Q28142778)

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For better or worse? Telomerase inhibition and cancer

scientific article (publication date: 6 August 1999)

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For better or worse? Telomerase inhibition and cancer (English)

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T de Lange

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T Jacks

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English

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publication date

6 August 1999

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273-5

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cites work

Functional characterization and developmental regulation of mouse telomerase RNA.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981955-8

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7 January 2021

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981955-8

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The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981955-8

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p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981955-8

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The RNA component of human telomerase

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Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

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Telomeres shorten during ageing of human fibroblasts

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Human telomeres: fusion and interstitial sites.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981955-8

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p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

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Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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Essential role of mouse telomerase in highly proliferative organs

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Severe growth defect in mouse cells lacking the telomerase RNA component

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A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

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Developmental and tissue-specific regulation of mouse telomerase and telomere length

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Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

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A survey of telomerase activity in human cancer

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981955-8

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TRF2 Protects Human Telomeres from End-to-End Fusions

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981955-8

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Identifiers

DOI

10.1016/S0092-8674(00)81955-8

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PubMed publication ID

10458601

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