(Q34535672)

2 August 2017

1 reference

title

Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis (English)

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2 August 2017

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2 August 2017

Jennifer A Hackett

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2 August 2017

language of work or name

English

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publication date

1 January 2002

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2 August 2017

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

619-626

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Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Protection of telomeres by the Ku protein in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Pot1, the putative telomere end-binding protein in fission yeast and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Ku binds telomeric DNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Cloning and expression of genes for the Oxytricha telomere-binding protein: specific subunit interactions in the telomeric complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Mammalian telomeres end in a large duplex loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Telomere dysfunction increases mutation rate and genomic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Inhibition of telomerase limits the growth of human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Telomeres shorten during ageing of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Ku is associated with the telomere in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Ku acts in a unique way at the mammalian telomere to prevent end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Development patterns of telomerase activity in barley and maize

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

A mutant with a defect in telomere elongation leads to senescence in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Telomere fusions caused by mutating the terminal region of telomeric DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Circular chromosome formation in a fission yeast mutant defective in two ATM homologues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Two modes of survival of fission yeast without telomerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

TRF2 Protects Human Telomeres from End-to-End Fusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Euplotes crassus has genes encoding telomere-binding proteins and telomere-binding protein homologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Structure and function of telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

7 January 2021

RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

7 January 2021

Mutations in the APC tumour suppressor gene cause chromosomal instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

7 January 2021

New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

7 January 2021

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

7 January 2021

A survey of telomerase activity in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

7 January 2021

Telomere positional effects and the regulation of cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205061

7 January 2021

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1038/SJ.ONC.1205061

Identifiers

DOI

10.1038/SJ.ONC.1205061

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Dimensions Publication ID

2 August 2017

1030779132

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1 reference