(Q28510138)

24 January 2017

title

Lack of the bone morphogenetic protein BMP6 induces massive iron overload (English)

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Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

24 January 2017

main subject

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Solute carrier family 40 (iron-regulated transporter), member 1

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SMAD family member 1

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SMAD family member 9

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Bone morphogenetic protein 6

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SMAD family member 5

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1 reference

1 reference

1 reference

Léon Kautz

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François Canonne-Hergaux

object named as

François Canonne-Hergaux

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Delphine Meynard

1 reference

24 January 2017

Valérie Darnaud

series ordinal

1 reference

24 January 2017

Hélène Coppin

series ordinal

1 reference

24 January 2017

Marie-Paule Roth

series ordinal

1 reference

24 January 2017

language of work or name

English

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publication date

1 April 2009

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24 January 2017

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24 January 2017

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24 January 2017

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24 January 2017

page(s)

478–481

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Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

24 January 2017

cites work

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Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6

21 April 2017

1 reference

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

21 April 2017

1 reference

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

21 April 2017

1 reference

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

21 April 2017

1 reference

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

21 April 2017

1 reference

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

21 April 2017

1 reference

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 April 2017

1 reference

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

21 April 2017

1 reference

A mouse model of juvenile hemochromatosis

21 April 2017

1 reference

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

21 April 2017

1 reference

Targeted disruption of the hepcidin 1 gene results in severe hemochromatosis

21 April 2017

1 reference

The family of bone morphogenetic proteins

21 April 2017

1 reference

Presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and down-regulated by hepcidin

21 April 2017

1 reference

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

21 April 2017

1 reference

A new mathematical model for relative quantification in real-time RT-PCR

21 April 2017

1 reference

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG.320

Hepcidin is decreased in TFR2 hemochromatosis

21 April 2017

1 reference

12 December 2020

Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders.

1 reference

12 December 2020

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

1 reference

12 December 2020

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

1 reference

12 December 2020

Hemochromatosis--neonatal and young subjects

1 reference

12 December 2020

Inactivation of the hemochromatosis gene differentially regulates duodenal expression of iron-related mRNAs between mouse strains

1 reference

12 December 2020

Mice lacking Bmp6 function

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12 December 2020

Bone morphogenetic proteins and their antagonists

1 reference

12 December 2020

Blunted hepcidin response to oral iron challenge in HFE-related hemochromatosis

1 reference

12 December 2020