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Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis
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Europe PubMed Central
title
Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis
(English)
1 reference
stated in
PubMed
author
Wenyi Wei
series ordinal
5
object named as
Wenyi Wei
1 reference
stated in
Crossref
Lixin Wan
series ordinal
2
object named as
Lixin Wan
1 reference
stated in
Crossref
author name string
Jinfang Zhang
series ordinal
1
1 reference
stated in
Crossref
Xiangpeng Dai
series ordinal
3
1 reference
stated in
Crossref
Yi Sun
series ordinal
4
1 reference
stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
April 2014
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stated in
PubMed
published in
Biochimica et Biophysica Acta
1 reference
stated in
PubMed
volume
1845
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stated in
PubMed
issue
2
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stated in
PubMed
page(s)
277-93
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stated in
PubMed
cites work
Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex
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The spindle assembly checkpoint
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21 March 2017
APC/C(Cdh1) targets brain-specific kinase 2 (BRSK2) for degradation via the ubiquitin-proteasome pathway
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21 March 2017
HECT and RING finger families of E3 ubiquitin ligases at a glance
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21 March 2017
Cell cycle control of Wnt/β-catenin signalling by conductin/axin2 through CDC20
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21 March 2017
K11-linked ubiquitin chains as novel regulators of cell division
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21 March 2017
RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
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21 March 2017
Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage
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21 March 2017
Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress
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21 March 2017
Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate
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21 March 2017
Control of cell growth by the SCF and APC/C ubiquitin ligases
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21 March 2017
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction
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21 March 2017
Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB
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21 March 2017
A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons
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21 March 2017
The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory
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21 March 2017
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation
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21 March 2017
The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint
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21 March 2017
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21 March 2017
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer
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21 March 2017
Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex
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21 March 2017
Functional importance of the anaphase-promoting complex-Cdh1-mediated degradation of TMAP/CKAP2 in regulation of spindle function and cytokinesis
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21 March 2017
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice
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21 March 2017
Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor
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21 March 2017
Cell-intrinsic regulation of axonal morphogenesis by the Cdh1-APC target SnoN
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21 March 2017
Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C
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21 March 2017
An architectural map of the anaphase-promoting complex
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21 March 2017
Multiple phosphorylation events control mitotic degradation of the muscle transcription factor Myf5.
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21 March 2017
Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint
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21 March 2017
Systematic analysis and nomenclature of mammalian F-box proteins
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21 March 2017
Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1
1 reference
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21 March 2017
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
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21 March 2017
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
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21 March 2017
Mitotic regulation of the human anaphase-promoting complex by phosphorylation
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21 March 2017
Alterations of anaphase-promoting complex genes in human colon cancer cells
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21 March 2017
E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)
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21 March 2017
Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex
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21 March 2017
APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex
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PubMed Central
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21 March 2017
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
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21 March 2017
MAD2B is an inhibitor of the anaphase-promoting complex
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21 March 2017
Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1
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21 March 2017
Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase
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21 March 2017
Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1
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21 March 2017
Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis
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21 March 2017
The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1
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21 March 2017
Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons
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21 March 2017
The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase
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21 March 2017
Geminin, an inhibitor of DNA replication, is degraded during mitosis
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21 March 2017
APC(CDH1) targets MgcRacGAP for destruction in the late M phase
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21 March 2017
Cdc20 Is Critical for Meiosis I and Fertility of Female Mice
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21 March 2017
RING domain E3 ubiquitin ligases
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21 March 2017
The spindle-assembly checkpoint in space and time
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21 March 2017
Mechanisms underlying ubiquitination
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21 March 2017
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity
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21 March 2017
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
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21 March 2017
The ubiquitin system
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21 March 2017
Pseudosubstrate inhibition of the anaphase-promoting complex by Acm1: regulation by proteolysis and Cdc28 phosphorylation
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21 March 2017
Modulation of the mitotic regulatory network by APC-dependent destruction of the Cdh1 inhibitor Acm1.
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21 March 2017
APC/C-Cdh1-mediated degradation of the Polo kinase Cdc5 promotes the return of Cdc14 into the nucleolus
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21 March 2017
Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase
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21 March 2017
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21 March 2017
Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex
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21 March 2017
Budding yeast Cdc20: a target of the spindle checkpoint.
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21 March 2017
Cohesins: chromosomal proteins that prevent premature separation of sister chromatids
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21 March 2017
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21 March 2017
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21 March 2017
Feedback control of mitosis in budding yeast
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21 March 2017
Cyclin is degraded by the ubiquitin pathway
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PubMed Central
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21 March 2017
Function and regulation of cullin-RING ubiquitin ligases
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21 March 2017
TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1
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21 March 2017
Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo
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21 March 2017
Regulation of APC-Cdc20 by the spindle checkpoint
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21 March 2017
The ubiquitin code
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21 March 2017
Expression of the mitotic checkpoint gene MAD2L2 has prognostic significance in colon cancer
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21 March 2017
The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint
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21 March 2017
The SCF ubiquitin ligase: insights into a molecular machine
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21 March 2017
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
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PubMed Central
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21 March 2017
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
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PubMed Central
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21 March 2017
Dual mode of degradation of Cdc25 A phosphatase
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PubMed Central
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21 March 2017
Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins
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21 March 2017
APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box
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PubMed Central
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21 March 2017
Map location and gene structure of the Homo sapiens mitotic arrest deficient 2 (MAD2L1) gene at 4q27
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21 March 2017
Identification of a cullin homology region in a subunit of the anaphase-promoting complex
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21 March 2017
Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores
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21 March 2017
A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation
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21 March 2017
Mouse emi1 has an essential function in mitotic progression during early embryogenesis
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21 March 2017
Increased chromosome instability but not cancer predisposition in haploinsufficient Bub3 mice
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21 March 2017
The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition
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21 March 2017
Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos
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21 March 2017
Mammalian Emi2 mediates cytostatic arrest and transduces the signal for meiotic exit via Cdc20.
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PubMed Central
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21 March 2017
Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability
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21 March 2017
Ink4a/Arf expression is a biomarker of aging
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21 March 2017
Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint
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21 March 2017
MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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21 March 2017
Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2
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PubMed Central
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21 March 2017
Mitotic regulation of the APC activator proteins CDC20 and CDH1
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PubMed Central
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21 March 2017
Studies on syndrome of diabetes insipidus associated with oligosyndactyly in mice
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21 March 2017
Shared principles in NF-kappaB signaling
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7 April 2017
Building ubiquitin chains: E2 enzymes at work
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7 April 2017
Physiological functions of the HECT family of ubiquitin ligases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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7 April 2017
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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7 April 2017
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
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7 April 2017
The anaphase promoting complex/cyclosome: a machine designed to destroy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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7 April 2017
Ubiquitin ligases: cell-cycle control and cancer
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PubMed Central
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7 April 2017
Diversity of gene expression in adenocarcinoma of the lung
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7 April 2017
Temporal and spatial control of cyclin B1 destruction in metaphase
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PubMed Central
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7 April 2017
Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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7 April 2017
ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress
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PubMed Central
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28 September 2017
The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
The phosphatase-transcription activator EYA1 is targeted by anaphase-promoting complex/Cdh1 for degradation at M-to-G1 transition.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
Cdc20: a potential novel therapeutic target for cancer treatment
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
Human KIAA1018/FAN1 nuclease is a new mitotic substrate of APC/C(Cdh1)
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages.
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28 September 2017
The ubiquitin system, an immense realm
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28 September 2017
The APC/C Ubiquitin Ligase: From Cell Biology to Tumorigenesis
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28 September 2017
The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis
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28 September 2017
Regulation of E2F1 by APC/C Cdh1 via K11 linkage-specific ubiquitin chain formation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
APC/C (Cdh1) controls the proteasome-mediated degradation of E2F3 during cell cycle exit
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1.
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28 September 2017
Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
Generation and physiological roles of linear ubiquitin chains
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28 September 2017
APC/C(Cdh1)-mediated degradation of the F-box protein NIPA is regulated by its association with Skp1
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.
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28 September 2017
Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells.
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28 September 2017
Structural insights into anaphase-promoting complex function and mechanism
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28 September 2017
Spindle assembly checkpoint: the third decade
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
APC(cdh1) mediates degradation of the oncogenic Rho-GEF Ect2 after mitosis.
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28 September 2017
Ubiquitin-dependent endocytosis, trafficking and turnover of neuronal membrane proteins
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28 September 2017
APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.
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PubMed Central
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28 September 2017
Anaphase promoting complex–dependent degradation of transcriptional repressors Nrm1 and Yhp1 inSaccharomyces cerevisiae
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
Akt isoform-specific signaling in breast cancer: uncovering an anti-migratory role for palladin
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28 September 2017
The emerging role of APC/CCdh1 in development
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28 September 2017
Mutual regulation between the spindle checkpoint and APC/C
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28 September 2017
Novel functions for the anaphase-promoting complex in neurobiology.
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28 September 2017
Mes1 controls the meiosis I to meiosis II transition by distinctly regulating the anaphase-promoting complex/cyclosome coactivators Fzr1/Mfr1 and Slp1 in fission yeast
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
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28 September 2017
Identification and validation of genes involved in cervical tumourigenesis
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28 September 2017
Structural basis for the subunit assembly of the anaphase-promoting complex
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28 September 2017
State of the APC/C: organization, function, and structure
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28 September 2017
SCF E3 Ubiquitin Ligases as Anticancer Targets
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28 September 2017
Assembly of k11-linked ubiquitin chains by the anaphase-promoting complex.
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28 September 2017
Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets
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28 September 2017
Degradation of the human mitotic checkpoint kinase Mps1 is cell cycle-regulated by APC-cCdc20 and APC-cCdh1 ubiquitin ligases
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28 September 2017
Interplay between Cdh1 and JNK activity during the cell cycle
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28 September 2017
The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.
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28 September 2017
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest.
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28 September 2017
Regulated degradation of spindle assembly factors by the anaphase-promoting complex.
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28 September 2017
Signaling to NF-kappaB: regulation by ubiquitination
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28 September 2017
Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal
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28 September 2017
Mitotic chromosomal instability and cancer: mouse modelling of the human disease.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
The anaphase-promoting complex/cyclosome (APC/C): cell-cycle-dependent and -independent functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Anaphase-promoting complex/cyclosome-cdh1 mediates the ubiquitination and degradation of TRB3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Ubiquitin ligase complexes: from substrate selectivity to conjugational specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Cdh1 controls the stability of TACC3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Therapeutic strategies within the ubiquitin proteasome system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Linear polyubiquitination: a new regulator of NF-kappaB activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
The role of ubiquitin in NF-kappaB regulatory pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Targeting the ubiquitin system in cancer therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Functionally distinct isoforms of Cik1 are differentially regulated by APC/C-mediated proteolysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Spindle assembly checkpoint and p53 deficiencies cooperate for tumorigenesis in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Ubiquitin in trafficking: the network at work
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
RCS1, a substrate of APC/C, controls the metaphase to anaphase transition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Anaphase-promoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Identification of yeast IQGAP (Iqg1p) as an anaphase-promoting-complex substrate and its role in actomyosin-ring-independent cytokinesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Human Kid is degraded by the APC/C(Cdh1) but not by the APC/C(Cdc20).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Cdc20: a WD40 activator for a cell cycle degradation machine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Cell cycle-dependent expression of centrosomal ninein-like protein in human cells is regulated by the anaphase-promoting complex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during mitotic exit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
KEN-box-dependent degradation of the Bub1 spindle checkpoint kinase by the anaphase-promoting complex/cyclosome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Cell cycle regulation of the human Six1 homeoprotein is mediated by APC(Cdh1).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
The regulation of INK4/ARF in cancer and aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
The CRY box: a second APCcdh1-dependent degron in mammalian cdc20.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Drug discovery in the ubiquitin-proteasome system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint and aneuploidization in oral cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Ubiquitylation and cell signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Cdh1/Hct1-APC is essential for the survival of postmitotic neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
The spindle checkpoint: tension versus attachment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Anillin is a substrate of anaphase-promoting complex/cyclosome (APC/C) that controls spatial contractility of myosin during late cytokinesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
APC/C regulation of axonal growth and synaptic functions in postmitotic neurons: the Liprin-alpha connection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
SCF-mediated protein degradation and cell cycle control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Spindle checkpoint protein dynamics at kinetochores in living cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
The spindle checkpoint, aneuploidy, and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Degradation of origin recognition complex large subunit by the anaphase-promoting complex in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
The anaphase-promoting complex: it's not just for mitosis any more.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Gene expression patterns in human liver cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Spindle checkpoint requires Mad1-bound and Mad1-free Mad2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Overexpression of murine fizzy-related (fzr) increases natural killer cell-mediated cell death and suppresses tumor growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Multiple regions of chromosome 4 demonstrating allelic losses in breast carcinomas.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
A transgene-induced mitotic arrest mutation in the mouse allelic with Oligosyndactylism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 September 2017
APC/C-Cdh1 coordinates neurogenesis and cortical size during development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
Acm1 contributes to nuclear positioning by inhibiting Cdh1-substrate interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
Regulation of APC/CCdc20 activity by RASSF1A-APC/CCdc20 circuitry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
MAD2 as a key component of mitotic checkpoint: A probable prognostic factor for gastric cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
Hiding human thymidine kinase 1 from APC/C-mediated destruction by thymidine binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
Genetic alterations in hepatocellular carcinomas: association between loss of chromosome 4q and p53 gene mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
31 May 2018
The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
APC/C(Cdh1)-dependent degradation of Cdc20 requires a phosphorylation on CRY-box by Polo-like kinase-1 during somatic cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Overexpression of CDC20 predicts poor prognosis in primary non-small cell lung cancer patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Cdc20 mediates D-box-dependent degradation of Sp100.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Structural biology: a new look for the APC.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
The anaphase promoting complex is required for memory function in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
APC/CCdh1 specific degradation of Hsl1 and Clb2 is required for proper stress responses of S. cerevisiae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Multiple anaphase-promoting complex/cyclosome degrons mediate the degradation of human Sgo1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Gene expression profiling in glioblastoma and immunohistochemical evaluation of IGFBP-2 and CDC20.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Genomic stability and tumour suppression by the APC/C cofactor Cdh1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Dissection of the APCCdh1-Skp2 cascade in breast cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
A mutual inhibition between APC/C and its substrate Mes1 required for meiotic progression in fission yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Cdc20 is required for the anaphase onset of the first meiosis but not the second meiosis in mouse oocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
The ubiquitin ligase APC(Cdh1) is required to maintain genome integrity in primary human cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Aging-associated vascular phenotype in mutant mice with low levels of BubR1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
The anaphase-promoting complex/cyclosome inhibitor Emi2 is essential for meiotic but not mitotic cell cycles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Mutant mice with small amounts of BubR1 display accelerated age-related gliosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
In vitro FRAP identifies the minimal requirements for Mad2 kinetochore dynamics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Destruction box-dependent degradation of aurora B is mediated by the anaphase-promoting complex/cyclosome and Cdh1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Independent regulation of synaptic size and activity by the anaphase-promoting complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Cdh1-APC controls axonal growth and patterning in the mammalian brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
BUBR1 deficiency results in abnormal megakaryopoiesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
S-phase checkpoint controls mitosis via an APC-independent Cdc20p function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Expression profiling of primary non-small cell lung cancer for target identification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
The cyclin-ubiquitin ligase activity of cyclosome/APC is jointly activated by protein kinases Cdk1-cyclin B and Plk.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Disruption of Apc10/Doc1 in three alleles of oligosyndactylism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
The anaphase-promoting complex is required in G1 arrested yeast cells to inhibit B-type cyclin accumulation and to prevent uncontrolled entry into S-phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Oligosyndactyly: a lethal mutation in the mouse that results in mitotic arrest very early in development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Oligosyndactylism, an early embryonic lethal in the mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3995847
retrieved
28 November 2018
Aberrant MAD2 expression in soft-tissue sarcoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ubiquitin signalling in DNA replication and repair
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Clinicopathologic significance of mitotic arrest defective protein 2 overexpression in hepatocellular carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression of Apc2 during mouse development
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Degradation of human RAP80 is cell cycle regulated by Cdc20 and Cdh1 ubiquitin ligases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Overexpression of MAD2 predicts clinical outcome in primary lung cancer patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Anaphase-promoting complex/cyclosome controls HEC1 stability
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Novel multiubiquitin chain linkages catalyzed by the conjugating enzymes E2EPF and RAD6 are recognized by 26 S proteasome subunit 5
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24569229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BBCAN.2014.02.001
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
100896
OpenCitations bibliographic resource ID
100896
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
100896
PMC publication ID
3995847
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
100896
PubMed publication ID
24569229
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
100896
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