(Q24303577)

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Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20951947%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage (English)

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15 February 2020

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methyl p-toluenesulfonyl-L-argininate

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ChEBI release 2020-05-28

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Shantanu K Gaur

3

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15 February 2020

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Xing Zeng

1

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15 February 2020

Frederic Sigoillot

2

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15 February 2020

Sungwoon Choi

4

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15 February 2020

Kathleen L Pfaff

5

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15 February 2020

Dong-Chan Oh

6

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Europe PubMed Central

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15 February 2020

Nathaniel Hathaway

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20951947%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Nevena Dimova

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20951947%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Gregory D Cuny

9

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Europe PubMed Central

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15 February 2020

Randall W King

10

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Europe PubMed Central

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15 February 2020

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publication date

1 October 2010

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15 February 2020

number of pages

14

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Europe PubMed Central

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15 February 2020

18

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Europe PubMed Central

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15 February 2020

4

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Europe PubMed Central

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15 February 2020

382-395

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20951947%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

The conserved KMN network constitutes the core microtubule-binding site of the kinetochore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

An architectural map of the anaphase-promoting complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

The spindle checkpoint requires cyclin-dependent kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

The spindle-assembly checkpoint in space and time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

19 March 2017

Kinetochore microtubule dynamics and attachment stability are regulated by Hec1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

7 April 2017

The anaphase promoting complex/cyclosome: a machine designed to destroy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

7 April 2017

Temporal and spatial control of cyclin B1 destruction in metaphase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

7 April 2017

Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

27 September 2017

Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

27 September 2017

APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

27 September 2017

Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

27 September 2017

Cdc20 and Cks direct the spindle checkpoint-independent destruction of cyclin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

27 September 2017

Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

27 September 2017

Cdc20: a WD40 activator for a cell cycle degradation machine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

27 September 2017

KEN-box-dependent degradation of the Bub1 spindle checkpoint kinase by the anaphase-promoting complex/cyclosome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

27 September 2017

Assembly of an APC-Cdh1-substrate complex is stimulated by engagement of a destruction box.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

27 September 2017

Docetaxel for treatment of solid tumours: a systematic review of clinical data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

27 September 2017

Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

30 May 2018

Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

30 May 2018

Requirement for proteolysis in spindle assembly checkpoint silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

29 November 2018

Length of mitotic arrest induced by microtubule-stabilizing drugs determines cell death after mitotic exit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

29 November 2018

Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

29 November 2018

The ubiquitin ligase APC(Cdh1) is required to maintain genome integrity in primary human cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

29 November 2018

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

29 November 2018

Destruction box-dependent degradation of aurora B is mediated by the anaphase-promoting complex/cyclosome and Cdh1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

29 November 2018

Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

29 November 2018

Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

29 November 2018

A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957475

29 November 2018

An inhibitor of the chymotrypsin-like activity of the multicatalytic proteinase complex (20S proteasome) induces arrest in G2-phase and metaphase in HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20951947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anaphase inactivation of the spindle checkpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/20951947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aurora B kinase-dependent recruitment of hZW10 and hROD to tensionless kinetochores

1 reference

https://pubmed.ncbi.nlm.nih.gov/20951947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Role for the Fizzy/Cdc20 Family of Proteins in Activation of the APC/C Distinct from Substrate Recruitment

1 reference

https://pubmed.ncbi.nlm.nih.gov/20951947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CCR.2010.08.010

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20951947%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20951947%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20951947%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

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