(Q37325110)

19 August 2017

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title

Ubiquitin in trafficking: the network at work (English)

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19 August 2017

Filippo Acconcia

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19 August 2017

Sara Sigismund

series ordinal

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19 August 2017

Simona Polo

series ordinal

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19 August 2017

language of work or name

English

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publication date

28 October 2008

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Experimental Cell Research

19 August 2017

published in

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19 August 2017

volume

315

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19 August 2017

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19 August 2017

page(s)

1610-1618

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Changing venues for tumour suppression: balancing destruction and localization by monoubiquitylation

19 August 2017

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Polyubiquitin chains: polymeric protein signals

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Ubiquitin-binding domains

7 January 2021

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Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis

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The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants.

7 January 2021

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Ubiquitin Lys63 is involved in ubiquitination of a yeast plasma membrane protein

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Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

7 January 2021

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Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

7 January 2021

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Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting

7 January 2021

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Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation

7 January 2021

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Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein

7 January 2021

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From Tpr-Met to Met, tumorigenesis and tubes.

7 January 2021

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Distinct turnover of alternatively spliced isoforms of the RET kinase receptor mediated by differential recruitment of the Cbl ubiquitin ligase

7 January 2021

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Defective downregulation of receptor tyrosine kinases in cancer

7 January 2021

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Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis

7 January 2021

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Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

7 January 2021

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Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

7 January 2021

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EGF receptor ubiquitination is not necessary for its internalization

7 January 2021

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Clathrin-independent endocytosis of ubiquitinated cargos

7 January 2021

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Cbl-mediated Ubiquitinylation Is Required for Lysosomal Sorting of Epidermal Growth Factor Receptor but Is Dispensable for Endocytosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Cargo recognition during clathrin-mediated endocytosis: a team effort

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Molecular mechanisms of coupled monoubiquitination

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Proliferation versus migration in platelet-derived growth factor signaling: the key role of endocytosis.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Endocytosis, endosome trafficking, and the regulation of Drosophila development

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Regulation of activin/nodal signaling by Rap2-directed receptor trafficking

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Cell Survival through Trk Neurotrophin Receptors Is Differentially Regulated by Ubiquitination

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Functions and mechanisms of retrograde neurotrophin signalling

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The roles of receptor and ligand endocytosis in regulating Notch signaling

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Endocytosis conducts the cell signaling orchestra

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin

7 January 2021

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A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling

7 January 2021

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E3-independent monoubiquitination of ubiquitin-binding proteins.

7 January 2021

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Regulation of ubiquitin-binding proteins by monoubiquitination

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

7 January 2021

1 reference

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Ubiquitin-dependent sorting of integral membrane proteins for degradation in lysosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The emerging shape of the ESCRT machinery

7 January 2021

1 reference

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Integrated Structural Model and Membrane Targeting Mechanism of the Human ESCRT-II Complex

7 January 2021

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ESCRT complexes and the biogenesis of multivesicular bodies

7 January 2021

1 reference

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ESCRT-III family members stimulate Vps4 ATPase activity directly or via Vta1.

7 January 2021

1 reference

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Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Helical structures of ESCRT-III are disassembled by VPS4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

AMSH is an endosome-associated ubiquitin isopeptidase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Riding the DUBway: regulation of protein trafficking by deubiquitylating enzymes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The deubiquitinating enzyme Ubp1 affects sorting of the ATP-binding cassette-transporter Ste6 in the endocytic pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Rapid Ca2+-dependent decrease of protein ubiquitination at synapses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-catenin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The met receptor degradation pathway: requirement for Lys48-linked polyubiquitin independent of proteasome activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The c-Cbl/CD2AP complex regulates VEGF-induced endocytosis and degradation of Flt-1 (VEGFR-1)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.10.014

10.1016/J.YEXCR.2008.10.014

7 January 2021

Identifiers

DOI

1 reference

19 August 2017

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