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Measuring the Epidemiological Impact of a False Negative : Evidence from a Natural Experiment

Author

Listed:
  • Fetzer, Thiemo

    (University of Warwick, CAGE, CESifo and CEPR)

Abstract
Reliable COVID-19 testing remains a central pillar to manage the pandemic. Yet, the accuracy and reliability of tests and test equipment has regularly been brought into question. Both false-positive and false-negative test results convey costs. Yet, false negatives are likely more problematic due to the risk of onward transmission and the failure to break infection chains as a result. This paper studies the epidemiological impact of a false negative in the context of a high vaccine uptake country. Between 2 September and 12 October an estimated 43,000 PCR tests in the UK may have produced a false negative test result with individuals infected being told that they tested negative. These instances were particularly pronounced in the South West of England. Using a synthetic control method approach concentrating on the 13 most affected regions, this paper estimates that every false negative COVID-19 case is likely to have caused between 0.6 to 1.6 additional infections in the subsequent weeks

Suggested Citation

  • Fetzer, Thiemo, 2021. "Measuring the Epidemiological Impact of a False Negative : Evidence from a Natural Experiment," The Warwick Economics Research Paper Series (TWERPS) 1386, University of Warwick, Department of Economics.
  • Handle: RePEc:wrk:warwec:1386
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    File URL: https://warwick.ac.uk/fac/soc/economics/research/workingpapers/2021/twerp_1386_-_fetzer.pdf
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    References listed on IDEAS

    as
    1. Timo Mitze & Reinhold Kosfeld & Johannes Rode & Klaus Wälde, 2020. "Face Masks Considerably Reduce Covid-19 Cases in Germany," Working Papers 2016, Gutenberg School of Management and Economics, Johannes Gutenberg-Universität Mainz.
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    4. Alberto Abadie & Alexis Diamond & Jens Hainmueller, 2015. "Comparative Politics and the Synthetic Control Method," American Journal of Political Science, John Wiley & Sons, vol. 59(2), pages 495-510, February.
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    6. Mitze, Timo & Kosfeld, Reinhold & Rode, Johannes & Wälde, Klaus, 2020. "Face masks considerably reduce COVID-19 cases in Germany," Publications of Darmstadt Technical University, Institute for Business Studies (BWL) 124130, Darmstadt Technical University, Department of Business Administration, Economics and Law, Institute for Business Studies (BWL).
    7. Thiemo Fetzer & Thomas Graeber, 2021. "Measuring the scientific effectiveness of contact tracing: Evidence from a natural experiment," Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences, vol. 118(33), pages 2100814118-, August.
    Full references (including those not matched with items on IDEAS)

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    More about this item

    Keywords

    False Negative ; Natural Experiment ; Test Error ; Health ; Coronavirus JEL Classification: I31 ; Z18;
    All these keywords.

    JEL classification:

    • I31 - Health, Education, and Welfare - - Welfare, Well-Being, and Poverty - - - General Welfare, Well-Being
    • Z1 - Other Special Topics - - Cultural Economics

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