Comprehensive design of CRISPR gRNAs for nucleases and base editors
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Updated
Jul 18, 2024 - R
Comprehensive design of CRISPR gRNAs for nucleases and base editors
A workflow to analyse sequence mutations in CRISPR-CAS9 targeted amplicon sequencing data
CB2 is an R package which provides functions for hit gene identification and quantification of sgRNA (single-guided RNA) abundances for CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) pooled screen data analysis. Details are in Jeong et al. (2019) <doi:10.1101/gr.245571.118> and Baggerly et al. (2003) <doi:10.1093/bioinformati…
Base functions and classes for CRISPR gRNA design
Useful human and mouse data for the crisprVerse ecosystem
Bowtie-based alignment of CRISPR gRNA spacer sequences
Pre-trained models for the crisprScore package
BWA-based alignment of CRISPR gRNA spacer sequences
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