The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis (Q92780795)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

title

The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis (English)

1 reference

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1 May 2020

1 reference

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1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Michelle A Mintz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

James H Felce

1 reference

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1 May 2020

Marissa Y Chou

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Ying Xu

1 reference

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1 May 2020

Jr-Wen Shui

1 reference

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1 May 2020

Jinping An

1 reference

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1 May 2020

Zhongmei Li

1 reference

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1 May 2020

Alexander Marson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Takaharu Okada

1 reference

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1 May 2020

Carl F Ware

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Mitchell Kronenberg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Jason G Cyster

1 reference

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1 May 2020

publication date

13 June 2019

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1 May 2020

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1 May 2020

volume

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1 May 2020

issue

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1 May 2020

page(s)

310-323.e7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6703922/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

DESeq2

object named as

Deseq2

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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11 February 2021

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Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells

11 February 2021

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Germinal Center B Cell Dynamics

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The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses

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Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses

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11 February 2021

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Highly Efficient Mouse Genome Editing by CRISPR Ribonucleoprotein Electroporation of Zygotes

11 February 2021

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11 February 2021

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11 February 2021

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Clonal selection in the germinal centre by regulated proliferation and hypermutation

11 February 2021

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Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

11 February 2021

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EBI2-mediated bridging channel positioning supports splenic dendritic cell homeostasis and particulate antigen capture

11 February 2021

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Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility

11 February 2021

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11 February 2021

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The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers

11 February 2021

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The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry

11 February 2021

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HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria

11 February 2021

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Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.

11 February 2021

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11 February 2021

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Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4+ 8- thymocytes and invariant NKT cells but not in Treg cells

11 February 2021

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The signaling networks of the herpesvirus entry mediator (TNFRSF14) in immune regulation

11 February 2021

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High rate of TNFRSF14 gene alterations related to 1p36 region in de novo follicular lymphoma and impact on prognosis

11 February 2021

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The microenvironment in follicular lymphoma

11 February 2021

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A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center

11 February 2021

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Acquired TNFRSF14 mutations in follicular lymphoma are associated with worse prognosis.

11 February 2021

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B and T Lymphocyte Attenuator Suppresses IL-21 Production from Follicular Th Cells and Subsequent Humoral Immune Responses

11 February 2021

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T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment

11 February 2021

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Activation-induced accumulation of B and T lymphocyte attenuator at the immunological synapse in CD4+ T cells

11 February 2021

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Bcl6 mediates the development of T follicular helper cells

11 February 2021

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Unconventional ligand activation of herpesvirus entry mediator signals cell survival

11 February 2021

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B and T lymphocyte attenuator regulates B cell receptor signaling by targeting Syk and BLNK.

11 February 2021

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CD40-CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells

11 February 2021

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Development of autoimmune hepatitis-like disease and production of autoantibodies to nuclear antigens in mice lacking B and T lymphocyte attenuator

11 February 2021

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Supported Planar Bilayers for Study of the Immunological Synapse

11 February 2021

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Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors

11 February 2021

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B and T lymphocyte attenuator interacts with CD3zeta and inhibits tyrosine phosphorylation of TCRzeta complex during T-cell activation

11 February 2021

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Preformed CD40 ligand exists in secretory lysosomes in effector and memory CD4+ T cells and is quickly expressed on the cell surface in an antigen-specific manner

11 February 2021

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Imaging of germinal center selection events during affinity maturation

11 February 2021

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Balancing co-stimulation and inhibition with BTLA and HVEM.

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

11 February 2021

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Functional validation of genes implicated in lymphomagenesis: an in vivo selection assay using a Myc-induced B-cell tumor

11 February 2021

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses

11 February 2021

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B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator

11 February 2021

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Immunological synapse formation licenses CD40-CD40L accumulations at T-APC contact sites

11 February 2021

1 reference

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SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

11 February 2021

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Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

The antigen dose determines T helper subset development by regulation of CD40 ligand

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

Experimental analysis by site-directed mutagenesis of somatic mutation effects on affinity and fine specificity in antibodies specific for lysozyme

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6703922

10.1016/J.IMMUNI.2019.05.022

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

PubMed publication ID

31204070

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31204070%20AND%20SRC:MED&resulttype=core&format=json