Perspectives on In Vitro to In Vivo Extrapolations (Q92345127)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31890748%20AND%20SRC:MED&resulttype=core&format=json

29 April 2020

review article

1 reference

title

Perspectives on In Vitro to In Vivo Extrapolations (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31890748%20AND%20SRC:MED&resulttype=core&format=json

29 April 2020

Thomas Hartung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31890748%20AND%20SRC:MED&resulttype=core&format=json

29 April 2020

publication date

8 December 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31890748%20AND%20SRC:MED&resulttype=core&format=json

Applied In Vitro Toxicology

29 April 2020

published in

1 reference

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29 April 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31890748%20AND%20SRC:MED&resulttype=core&format=json

29 April 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31890748%20AND%20SRC:MED&resulttype=core&format=json

29 April 2020

page(s)

305-316

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31890748%20AND%20SRC:MED&resulttype=core&format=json

A primer on systematic reviews in toxicology.

29 April 2020

cites work

1 reference

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A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity

23 February 2021

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Evidence-based absorption, distribution, metabolism, excretion (ADME) and its interplay with alternative toxicity methods.

23 February 2021

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Good Cell Culture Practice for stem cells and stem-cell-derived models.

23 February 2021

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Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function

23 February 2021

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The Emergence of Systematic Review in Toxicology

23 February 2021

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Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

23 February 2021

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Analysis of the Local Lymph Node Assay (LLNA) variability for assessing the prediction of skin sensitisation potential and potency of chemicals with non-animal approaches

23 February 2021

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Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review.

23 February 2021

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Making big sense from big data in toxicology by read-across

23 February 2021

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Toward Good Read-Across Practice (GRAP) guidance

23 February 2021

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Analysis of publically available skin sensitization data from REACH registrations 2008-2014

23 February 2021

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Analysis of Draize eye irritation testing and its prediction by mining publicly available 2008-2014 REACH data

23 February 2021

1 reference

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A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis.

23 February 2021

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23 February 2021

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LLNA variability: An essential ingredient for a comprehensive assessment of non-animal skin sensitization test methods and strategies

23 February 2021

1 reference

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MPTP's pathway of toxicity indicates central role of transcription factor SP1.

23 February 2021

1 reference

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Systems Toxicology: The Future of Risk Assessment

23 February 2021

1 reference

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Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay

23 February 2021

1 reference

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Integrated Testing Strategies (ITS) for safety assessment.

23 February 2021

1 reference

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Read-across approaches--misconceptions, promises and challenges ahead

23 February 2021

1 reference

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Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA).

23 February 2021

1 reference

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Developing microphysiological systems for use as regulatory tools--challenges and opportunities

23 February 2021

1 reference

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Consensus report on the future of animal-free systemic toxicity testing

23 February 2021

1 reference

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23 February 2021

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State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology

23 February 2021

1 reference

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Current approaches and future role of high content imaging in safety sciences and drug discovery

23 February 2021

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Biological and medical applications of a brain-on-a-chip

23 February 2021

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Glossary of reference terms for alternative test methods and their validation

23 February 2021

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Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+)

23 February 2021

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A framework for the next generation of risk science

23 February 2021

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3D - a new dimension of in vitro research

23 February 2021

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Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities

23 February 2021

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Toward a 3D model of human brain development for studying gene/environment interactions

23 February 2021

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Building shared experience to advance practical application of pathway-based toxicology: liver toxicity mode-of-action

23 February 2021

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Systems toxicology: from basic research to risk assessment

23 February 2021

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Mapping the human toxome by systems toxicology.

23 February 2021

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Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods

23 February 2021

1 reference

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Correlating in vitro data to in vivo findings for risk assessment

23 February 2021

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t4 workshop report: Pathways of Toxicity

23 February 2021

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Look back in anger - what clinical studies tell us about preclinical work

23 February 2021

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Review: toxicometabolomics

23 February 2021

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Metabolomics in toxicology and preclinical research

23 February 2021

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23 February 2021

Mechanistic validation.

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Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice

23 February 2021

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The new revolution in toxicology: the good, the bad, and the ugly.

23 February 2021

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Evidence-based toxicology for the 21st century: opportunities and challenges

23 February 2021

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Perspectives on validation of high-throughput assays supporting 21st century toxicity testing

23 February 2021

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Integrated testing strategies for safety assessments

23 February 2021

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The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans.

23 February 2021

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Towards tailored assays for cell-based approaches to toxicity testing

23 February 2021

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The GARD assay for assessment of chemical skin sensitizers

23 February 2021

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Alternative approaches for medical countermeasures to biological and chemical terrorism and warfare

23 February 2021

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23 February 2021

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Drug development: Raise standards for preclinical cancer research

23 February 2021

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A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report*.

23 February 2021

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Nanotoxicology: "the end of the beginning" - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterials

23 February 2021

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Integrating non-animal test information into an adaptive testing strategy - skin sensitization proof of concept case.

23 February 2021

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Believe it or not: how much can we rely on published data on potential drug targets?

23 February 2021

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Integrated testing strategies for toxicity employing new and existing technologies

23 February 2021

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Alternative in vitro assays in nanomaterial toxicology

23 February 2021

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Food for Thought ... on mapping the human toxome

23 February 2021

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Evidence-based toxicology – the toolbox of validation for the 21st century?

23 February 2021

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Integrated Testing Strategy (ITS) – Opportunities to better use existing data and guide future testing in toxicology

23 February 2021

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From alternative methods to a new toxicology

23 February 2021

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Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

23 February 2021

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Food for thought ... on alternative methods for nanoparticle safety testing

23 February 2021

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Lessons learned from alternative methods and their validation for a new toxicology in the 21st century

23 February 2021

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Toxicity testing in the 21st century: a vision and a strategy

23 February 2021

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Food for thought...on alternative methods for chemical safety testing

23 February 2021

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Food for thought ... on in silico methods in toxicology

23 February 2021

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Are in vitro tests suitable for regulatory use?

23 February 2021

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Toxicology for the twenty-first century

23 February 2021

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Food for thought... on evidence-based toxicology.

23 February 2021

1 reference

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"ToxRTool", a new tool to assess the reliability of toxicological data

23 February 2021

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A toxicology for the 21st century--mapping the road ahead

23 February 2021

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Food for thought... on the economics of animal testing

23 February 2021

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Points of reference in the validation process: the report and recommendations of ECVAM Workshop 66

23 February 2021

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The dawning of a new age of toxicology.

23 February 2021

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Food for thought ... on the evolution of toxicology and the phasing out of animal testing

23 February 2021

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Food for thought... on animal tests

23 February 2021

1 reference

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ECVAM retrospective validation of in vitro micronucleus test (MNT)

23 February 2021

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IPCS framework for analyzing the relevance of a noncancer mode of action for humans

23 February 2021

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Physiologically-based Kinetic Modelling (PBK Modelling): meeting the 3Rs agenda. The report and recommendations of ECVAM Workshop 63

23 February 2021

1 reference

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Food for thought... on cell culture.

23 February 2021

1 reference

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Food for thought ... on validation

23 February 2021

1 reference

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IPCS framework for analyzing the relevance of a cancer mode of action for humans.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6309130

Toward an evidence-based toxicology

23 February 2021

1 reference

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Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54

23 February 2021

1 reference

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Meeting report: Validation of toxicogenomics-based test systems: ECVAM-ICCVAM/NICEATM considerations for regulatory use.

23 February 2021

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Guidance on good cell culture practice. a report of the second ECVAM task force on good cell culture practice

23 February 2021

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Diagnosis: toxic!--trying to apply approaches of clinical diagnostics and prevalence in toxicology considerations

23 February 2021

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A modular approach to the ECVAM principles on test validity.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6309130

Where is the evidence that animal research benefits humans?

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6309130

The use and evaluation of primary data in 29 trichloroethylene carcinogen risk assessments

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6309130

Concordance of the toxicity of pharmaceuticals in humans and in animals

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6309130

Toxicity testing in the 21st century beyond environmental chemicals

23 February 2021

1 reference

15 October 2024

https://opencitations.net/index/api/v1/citations/10.14573/ALTEX.1506201

Bayesian network integrated testing strategy and beyond

1 reference

15 October 2024

https://opencitations.net/index/api/v1/citations/10.14573/ALTEX.2013.3.386

Comparative analysis of the revised Directive 2010/63/EU for the protection of laboratory animals with its predecessor 86/609/EEC – a t4 report

1 reference

15 October 2024

https://opencitations.net/index/api/v1/citations/10.14573/ALTEX.2010.4.285

Identifiers

DOI

10.1089/AIVT.2016.0026

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31890748%20AND%20SRC:MED&resulttype=core&format=json

29 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31890748%20AND%20SRC:MED&resulttype=core&format=json

29 April 2020

PubMed publication ID

31890748

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31890748%20AND%20SRC:MED&resulttype=core&format=json