Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+) (Q33720121)

28 July 2017

title

Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+) (English)

1 reference

28 July 2017

0 references

S Förster

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H Farhan

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M Leist

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A K Krug

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28 July 2017

S Gutbier

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28 July 2017

L Zhao

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28 July 2017

D Pöltl

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28 July 2017

C Kullmann

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28 July 2017

V Ivanova

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28 July 2017

S Jagtap

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28 July 2017

J Meiser

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28 July 2017

G Leparc

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28 July 2017

S Schildknecht

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28 July 2017

M Adam

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28 July 2017

K Hiller

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28 July 2017

T Brunner

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28 July 2017

T Hartung

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28 July 2017

A Sachinidis

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28 July 2017

language of work or name

1 reference

8 May 2014

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28 July 2017

published in

Cell Death and Disease

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28 July 2017

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28 July 2017

page(s)

e1222

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

28 July 2017

start time

1 May 2014

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

describes a project that uses

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4047858

based on heuristic

inferred from PubMed Central ID database lookup

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo

21 June 2018

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21 June 2018

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1-methyl-4-phenylpyridinium-induced alterations of glutathione status in immortalized rat dopaminergic neurons

21 June 2018

1 reference

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Anti-apoptotic gene therapy in Parkinson's disease

21 June 2018

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21 June 2018

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Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway.

21 June 2018

1 reference

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21 June 2018

1 reference

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Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons

21 June 2018

1 reference

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ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047858

MPTP-induced parkinsonism in human and non-human primates--clinical and experimental aspects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047858

Biology of disease: free radicals and tissue injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047858

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047858

Temporal concordance between apical and transcriptional points of departure for chemical risk assessment.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047858

Microtubule dysfunction precedes transport impairment and mitochondria damage in MPP+ -induced neurodegeneration

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047858

Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047858

AiO, combining DNA/protein programs and oligo-management

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047858

Effect of 1-methyl-4-phenylpyridinium on glutathione in rat pheochromocytoma PC 12 cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047858

MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24810058

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Correlation between 1-methyl-4-phenylpyridinium ion (MPP+) levels, ascorbic acid oxidation and glutathione levels in the striatal synaptosomes of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated rat

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24810058

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDDIS.2014.166

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference